Murakata C - Search Results

1

Synthesis and antitumor activity of novel O-carbamoylmethyloxime derivatives of radicicol.

Ikuina Y, Amishiro N, Miyata M, Narumi H, Ogawa H, Akiyama T, Shiotsu Y, Akinaga S, Murakata C. Ikuina Y, et al. Among authors: murakata c. J Med Chem. 2003 Jun 5;46(12):2534-41. doi: 10.1021/jm030110r. J Med Chem. 2003. PMID: 12773056

2

Synthetic studies on mitotic kinesin Eg5 inhibitors: synthesis and structure-activity relationships of novel 2,4,5-substituted-1,3,4-thiadiazoline derivatives.

Yamamoto J, Amishiro N, Kato K, Ohta Y, Ino Y, Araki M, Tsujita T, Okamoto S, Takahashi T, Kusaka H, Akinaga S, Yamashita Y, Nakai R, Murakata C. Yamamoto J, et al. Among authors: murakata c. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3961-3. doi: 10.1016/j.bmcl.2014.06.034. Epub 2014 Jun 20. Bioorg Med Chem Lett. 2014. PMID: 25001485

3

KF25706, a novel oxime derivative of radicicol, exhibits in vivo antitumor activity via selective depletion of Hsp90 binding signaling molecules.

Soga S, Neckers LM, Schulte TW, Shiotsu Y, Akasaka K, Narumi H, Agatsuma T, Ikuina Y, Murakata C, Tamaoki T, Akinaga S. Soga S, et al. Among authors: murakata c. Cancer Res. 1999 Jun 15;59(12):2931-8. Cancer Res. 1999. PMID: 10383157

4

Synthesis and antitumor activity of duocarmycin derivatives: modification of segment-A of A-ring pyrrole compounds.

Amishiro N, Okamoto A, Murakata C, Tamaoki T, Okabe M, Saito H. Amishiro N, et al. Among authors: murakata c. J Med Chem. 1999 Jul 29;42(15):2946-60. doi: 10.1021/jm990094r. J Med Chem. 1999. PMID: 10425104

5

Synthesis and antitumor activity of duocarmycin derivatives: modification at C-8 position of A-ring pyrrole compounds bearing the simplified DNA-binding groups.

Amishiro N, Nagamura S, Murakata C, Okamoto A, Kobayashi E, Asada M, Gomi K, Tamaoki T, Okabe M, Yamaguchi N, Yamaguchi K, Saito H. Amishiro N, et al. Among authors: murakata c. Bioorg Med Chem. 2000 Feb;8(2):381-91. doi: 10.1016/s0968-0896(99)00293-x. Bioorg Med Chem. 2000. PMID: 10722161

6

Stereospecific antitumor activity of radicicol oxime derivatives.

Soga S, Sharma SV, Shiotsu Y, Shimizu M, Tahara H, Yamaguchi K, Ikuina Y, Murakata C, Tamaoki T, Kurebayashi J, Schulte TW, Neckers LM, Akinaga S. Soga S, et al. Among authors: murakata c. Cancer Chemother Pharmacol. 2001 Dec;48(6):435-45. doi: 10.1007/s002800100373. Cancer Chemother Pharmacol. 2001. PMID: 11800023

7

Antitumor effect of KT6124, a novel derivative of protein kinase inhibitor K-252a, and its mechanism of action.

Akinaga S, Ashizawa T, Gomi K, Ohno H, Morimoto M, Murakata C, Okabe M. Akinaga S, et al. Among authors: murakata c. Cancer Chemother Pharmacol. 1992;29(4):266-72. doi: 10.1007/BF00685943. Cancer Chemother Pharmacol. 1992. PMID: 1537071

8

Novel oxime derivatives of radicicol induce erythroid differentiation associated with preferential G(1) phase accumulation against chronic myelogenous leukemia cells through destabilization of Bcr-Abl with Hsp90 complex.

Shiotsu Y, Neckers LM, Wortman I, An WG, Schulte TW, Soga S, Murakata C, Tamaoki T, Akinaga S. Shiotsu Y, et al. Among authors: murakata c. Blood. 2000 Sep 15;96(6):2284-91. Blood. 2000. PMID: 10979978 Free article.

9

Role of steroid sulfatase in local formation of estrogen in post-menopausal breast cancer patients.

Nakata T, Takashima S, Shiotsu Y, Murakata C, Ishida H, Akinaga S, Li PK, Sasano H, Suzuki T, Saeki T. Nakata T, et al. Among authors: murakata c. J Steroid Biochem Mol Biol. 2003 Sep;86(3-5):455-60. doi: 10.1016/s0960-0760(03)00357-1. J Steroid Biochem Mol Biol. 2003. PMID: 14623544

10

A novel steroidal selective steroid sulfatase inhibitor KW-2581 inhibits sulfated-estrogen dependent growth of breast cancer cells in vitro and in animal models.

Ishida H, Nakata T, Suzuki M, Shiotsu Y, Tanaka H, Sato N, Terasaki Y, Takebayashi M, Anazawa H, Murakata C, Li PK, Kuwabara T, Akinaga S. Ishida H, et al. Among authors: murakata c. Breast Cancer Res Treat. 2007 Dec;106(2):215-27. doi: 10.1007/s10549-007-9495-x. Epub 2007 Feb 1. Breast Cancer Res Treat. 2007. PMID: 17268815

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