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Targeted disruption of the murine Bin1/Amphiphysin II gene does not disable endocytosis but results in embryonic cardiomyopathy with aberrant myofibril formation.
Muller AJ, Baker JF, DuHadaway JB, Ge K, Farmer G, Donover PS, Meade R, Reid C, Grzanna R, Roach AH, Shah N, Soler AP, Prendergast GC. Muller AJ, et al. Among authors: soler ap. Mol Cell Biol. 2003 Jun;23(12):4295-306. doi: 10.1128/MCB.23.12.4295-4306.2003. Mol Cell Biol. 2003. PMID: 12773571 Free PMC article.
Bin3 deletion causes cataracts and increased susceptibility to lymphoma during aging.
Ramalingam A, Duhadaway JB, Sutanto-Ward E, Wang Y, Dinchuk J, Huang M, Donover PS, Boulden J, McNally LM, Soler AP, Muller AJ, Duncan MK, Prendergast GC. Ramalingam A, et al. Among authors: soler ap. Cancer Res. 2008 Mar 15;68(6):1683-90. doi: 10.1158/0008-5472.CAN-07-6072. Cancer Res. 2008. PMID: 18339847
Non-hematopoietic expression of IDO is integrally required for inflammatory tumor promotion.
Muller AJ, DuHadaway JB, Chang MY, Ramalingam A, Sutanto-Ward E, Boulden J, Soler AP, Mandik-Nayak L, Gilmour SK, Prendergast GC. Muller AJ, et al. Among authors: soler ap. Cancer Immunol Immunother. 2010 Nov;59(11):1655-63. doi: 10.1007/s00262-010-0891-4. Epub 2010 Jul 17. Cancer Immunol Immunother. 2010. PMID: 20640572 Free PMC article.
Chronic inflammation that facilitates tumor progression creates local immune suppression by inducing indoleamine 2,3 dioxygenase.
Muller AJ, Sharma MD, Chandler PR, Duhadaway JB, Everhart ME, Johnson BA 3rd, Kahler DJ, Pihkala J, Soler AP, Munn DH, Prendergast GC, Mellor AL. Muller AJ, et al. Among authors: soler ap. Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):17073-8. doi: 10.1073/pnas.0806173105. Epub 2008 Oct 24. Proc Natl Acad Sci U S A. 2008. PMID: 18952840 Free PMC article.
IDO is a nodal pathogenic driver of lung cancer and metastasis development.
Smith C, Chang MY, Parker KH, Beury DW, DuHadaway JB, Flick HE, Boulden J, Sutanto-Ward E, Soler AP, Laury-Kleintop LD, Mandik-Nayak L, Metz R, Ostrand-Rosenberg S, Prendergast GC, Muller AJ. Smith C, et al. Among authors: soler ap. Cancer Discov. 2012 Aug;2(8):722-35. doi: 10.1158/2159-8290.CD-12-0014. Epub 2012 Jul 19. Cancer Discov. 2012. PMID: 22822050 Free PMC article.
68 results