Steenkamp DJ - Search Results

1

Synthesis of 2-deoxy-2-C-alkylglucosides of myo-inositol as possible inhibitors of a N-deacetylase enzyme in the biosynthesis of mycothiol.

Gammon DW, Hunter R, Steenkamp DJ, Mudzunga TT. Gammon DW, et al. Among authors: steenkamp dj. Bioorg Med Chem Lett. 2003 Jun 16;13(12):2045-9. doi: 10.1016/s0960-894x(03)00157-4. Bioorg Med Chem Lett. 2003. PMID: 12781192

2

Synthesis of mycothiol, 1D-1-O-(2-[N-acetyl-L-cysteinyl]amino-2-deoxy-alpha-D-glucopyranosyl)-myo-inositol, principal low molecular mass thiol in the actinomycetes.

Jardine MA, Spies HS, Nkambule CM, Gammon DW, Steenkamp DJ. Jardine MA, et al. Among authors: steenkamp dj. Bioorg Med Chem. 2002 Apr;10(4):875-81. doi: 10.1016/s0968-0896(01)00383-2. Bioorg Med Chem. 2002. PMID: 11836093

3

Conjugates of plumbagin and phenyl-2-amino-1-thioglucoside inhibit MshB, a deacetylase involved in the biosynthesis of mycothiol.

Gammon DW, Steenkamp DJ, Mavumengwana V, Marakalala MJ, Mudzunga TT, Hunter R, Munyololo M. Gammon DW, et al. Among authors: steenkamp dj. Bioorg Med Chem. 2010 Apr 1;18(7):2501-14. doi: 10.1016/j.bmc.2010.02.049. Epub 2010 Mar 1. Bioorg Med Chem. 2010. PMID: 20304659

4

Biosynthesis of mycothiol: elucidation of the sequence of steps in Mycobacterium smegmatis.

Bornemann C, Jardine MA, Spies HS, Steenkamp DJ. Bornemann C, et al. Among authors: steenkamp dj. Biochem J. 1997 Aug 1;325 ( Pt 3)(Pt 3):623-9. doi: 10.1042/bj3250623. Biochem J. 1997. PMID: 9271081 Free PMC article.

5

Thiols of intracellular pathogens. Identification of ovothiol A in Leishmania donovani and structural analysis of a novel thiol from Mycobacterium bovis.

Spies HS, Steenkamp DJ. Spies HS, et al. Among authors: steenkamp dj. Eur J Biochem. 1994 Aug 15;224(1):203-13. doi: 10.1111/j.1432-1033.1994.tb20013.x. Eur J Biochem. 1994. PMID: 8076641 Free article.

6

The metabolism of nitrosothiols in the Mycobacteria: identification and characterization of S-nitrosomycothiol reductase.

Vogt RN, Steenkamp DJ, Zheng R, Blanchard JS. Vogt RN, et al. Among authors: steenkamp dj. Biochem J. 2003 Sep 15;374(Pt 3):657-66. doi: 10.1042/BJ20030642. Biochem J. 2003. PMID: 12809551 Free PMC article.

7

Preparation and utilization of a reagent for the isolation and purification of low-molecular-mass thiols.

Steenkamp DJ, Vogt RN. Steenkamp DJ, et al. Anal Biochem. 2004 Feb 1;325(1):21-7. doi: 10.1016/j.ab.2003.10.011. Anal Biochem. 2004. PMID: 14715280

8

A new crystal form of MshB from Mycobacterium tuberculosis with glycerol and acetate in the active site suggests the catalytic mechanism.

Broadley SG, Gumbart JC, Weber BW, Marakalala MJ, Steenkamp DJ, Sewell BT. Broadley SG, et al. Among authors: steenkamp dj. Acta Crystallogr D Biol Crystallogr. 2012 Nov;68(Pt 11):1450-9. doi: 10.1107/S090744491203449X. Epub 2012 Oct 13. Acta Crystallogr D Biol Crystallogr. 2012. PMID: 23090394

9

The effect of buthionine sulfoximine on the growth of Leishmania donovani in culture.

Weldrick DP, Chodacka B, Vogt R, Steenkamp DJ. Weldrick DP, et al. Among authors: steenkamp dj. FEMS Microbiol Lett. 1999 Apr 1;173(1):139-46. doi: 10.1111/j.1574-6968.1999.tb13495.x. FEMS Microbiol Lett. 1999. PMID: 10220890

10

Trypanosomal antioxidants and emerging aspects of redox regulation in the trypanosomatids.

Steenkamp DJ. Steenkamp DJ. Antioxid Redox Signal. 2002 Feb;4(1):105-21. doi: 10.1089/152308602753625906. Antioxid Redox Signal. 2002. PMID: 11970848 Review.

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