Morral J - Search Results

1

Synthesis and antiviral activity of a series of new cyclohexenyl nucleosides.

Gu P, Morral J, Wang J, Rozenski J, Busson R, Van Aerschot A, De Clercq E, Herdewijn P. Gu P, et al. Among authors: morral j. Antivir Chem Chemother. 2003 Jan;14(1):31-7. doi: 10.1177/095632020301400103. Antivir Chem Chemother. 2003. PMID: 12790514 Free article.

2

Synthesis and biological evaluation of a series of new cyclohexenyl nucleosides.

Gu P, Morral J, Wang J, Rozenski J, Busson R, Van Aerschot A, De Clercq E, Herdewijn P. Gu P, et al. Among authors: morral j. Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):845-7. doi: 10.1081/NCN-120022668. Nucleosides Nucleotides Nucleic Acids. 2003. PMID: 14565293

3

A straightforward stereoselective synthesis of D- and L-5-hydroxy-4-hydroxymethyl-2-cyclohexenylguanine.

Wang J, Morral J, Hendrix C, Herdewijn P. Wang J, et al. Among authors: morral j. J Org Chem. 2001 Dec 14;66(25):8478-82. doi: 10.1021/jo015924z. J Org Chem. 2001. PMID: 11735528

4

Design, synthesis, conformational analysis and nucleic acid hybridisation properties of thymidyl pyrrolidine-amide oligonucleotide mimics (POM).

Hickman DT, Tan TH, Morral J, King PM, Cooper MA, Micklefield J. Hickman DT, et al. Among authors: morral j. Org Biomol Chem. 2003 Oct 7;1(19):3277-92. doi: 10.1039/b306156f. Org Biomol Chem. 2003. PMID: 14584791

5

Mixed-sequence pyrrolidine-amide oligonucleotide mimics: Boc(Z) synthesis and DNA/RNA binding properties.

Worthington RJ, O'Rourke AP, Morral J, Tan TH, Micklefield J. Worthington RJ, et al. Among authors: morral j. Org Biomol Chem. 2007 Jan 21;5(2):249-59. doi: 10.1039/b613386j. Epub 2006 Dec 1. Org Biomol Chem. 2007. PMID: 17205168

6

Homopolymeric pyrrolidine-amide oligonucleotide mimics: Fmoc-synthesis and DNA/RNA binding properties.

Tan TH, Worthington RJ, Pritchard RG, Morral J, Micklefield J. Tan TH, et al. Among authors: morral j. Org Biomol Chem. 2007 Jan 21;5(2):239-48. doi: 10.1039/b613384n. Epub 2006 Dec 1. Org Biomol Chem. 2007. PMID: 17205167

7

Nucleic acid binding properties of thyminyl and adeninyl pyrrolidine-amide oligonucleotide mimics (POM).

Tan TH, Hickman DT, Morral J, Beadham IG, Micklefield J. Tan TH, et al. Among authors: morral j. Chem Commun (Camb). 2004 Mar 7;(5):516-7. doi: 10.1039/b315768g. Epub 2004 Jan 28. Chem Commun (Camb). 2004. PMID: 14973585

8

Synthesis, in vitro pharmacology, and molecular modeling of very potent tacrine-huperzine A hybrids as acetylcholinesterase inhibitors of potential interest for the treatment of Alzheimer's disease.

Camps P, El Achab R, Görbig DM, Morral J, Muñoz-Torrero D, Badia A, Eladi Baños J, Vivas NM, Barril X, Orozco M, Luque FJ. Camps P, et al. Among authors: morral j. J Med Chem. 1999 Aug 26;42(17):3227-42. doi: 10.1021/jm980620z. J Med Chem. 1999. PMID: 10464010

9

New tacrine-huperzine A hybrids (huprines): highly potent tight-binding acetylcholinesterase inhibitors of interest for the treatment of Alzheimer's disease.

Camps P, El Achab R, Morral J, Muñoz-Torrero D, Badia A, Baños JE, Vivas NM, Barril X, Orozco M, Luque FJ. Camps P, et al. Among authors: morral j. J Med Chem. 2000 Nov 30;43(24):4657-66. doi: 10.1021/jm000980y. J Med Chem. 2000. PMID: 11101357

10

Multigram scale synthesis of polycyclic lactones and evaluation of antitumor and other biological properties.

Grau L, Romero M, Privat-Contreras C, Presa D, Viñas M, Morral J, Pors K, Rubio-Martinez J, Pujol MD. Grau L, et al. Among authors: morral j. Eur J Med Chem. 2020 Jan 1;185:111807. doi: 10.1016/j.ejmech.2019.111807. Epub 2019 Oct 23. Eur J Med Chem. 2020. PMID: 31675512

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