Sklar LA - Search Results

1

Functional capabilities of an N-formyl peptide receptor-G(alpha)(i)(2) fusion protein: assemblies with G proteins and arrestins.

Shi M, Bennett TA, Cimino DF, Maestas DC, Foutz TD, Gurevich VV, Sklar LA, Prossnitz ER. Shi M, et al. Among authors: sklar la. Biochemistry. 2003 Jun 24;42(24):7283-93. doi: 10.1021/bi0341657. Biochemistry. 2003. PMID: 12809484

2

N-formyl peptide receptor phosphorylation domains differentially regulate arrestin and agonist affinity.

Key TA, Foutz TD, Gurevich VV, Sklar LA, Prossnitz ER. Key TA, et al. Among authors: sklar la. J Biol Chem. 2003 Feb 7;278(6):4041-7. doi: 10.1074/jbc.M204687200. Epub 2002 Nov 6. J Biol Chem. 2003. PMID: 12424254 Free article.

3

Ligand-receptor-G-protein molecular assemblies on beads for mechanistic studies and screening by flow cytometry.

Simons PC, Shi M, Foutz T, Cimino DF, Lewis J, Buranda T, Lim WK, Neubig RR, McIntire WE, Garrison J, Prossnitz E, Sklar LA. Simons PC, et al. Among authors: sklar la. Mol Pharmacol. 2003 Nov;64(5):1227-38. doi: 10.1124/mol.64.5.1227. Mol Pharmacol. 2003. PMID: 14573773

4

Inhibition of chemoattractant N-formyl peptide receptor trafficking by active arrestins.

Key TA, Vines CM, Wagener BM, Gurevich VV, Sklar LA, Prossnitz ER. Key TA, et al. Among authors: sklar la. Traffic. 2005 Feb;6(2):87-99. doi: 10.1111/j.1600-0854.2004.00248.x. Traffic. 2005. PMID: 15634210 Free article.

5

Rapid-mix flow cytometry measurements of subsecond regulation of G protein-coupled receptor ternary complex dynamics by guanine nucleotides.

Wu Y, Buranda T, Simons PC, Lopez GP, McIntire WE, Garrison JC, Prossnitz ER, Sklar LA. Wu Y, et al. Among authors: sklar la. Anal Biochem. 2007 Dec 1;371(1):10-20. doi: 10.1016/j.ab.2007.08.011. Epub 2007 Aug 14. Anal Biochem. 2007. PMID: 17904091 Free PMC article.

6

Arrestin variants display differential binding characteristics for the phosphorylated N-formyl peptide receptor carboxyl terminus.

Potter RM, Key TA, Gurevich VV, Sklar LA, Prossnitz ER. Potter RM, et al. Among authors: sklar la. J Biol Chem. 2002 Mar 15;277(11):8970-8. doi: 10.1074/jbc.M111086200. Epub 2002 Jan 3. J Biol Chem. 2002. PMID: 11777932 Free article.

7

Multiple activation steps of the N-formyl peptide receptor.

Prossnitz ER, Gilbert TL, Chiang S, Campbell JJ, Qin S, Newman W, Sklar LA, Ye RD. Prossnitz ER, et al. Among authors: sklar la. Biochemistry. 1999 Feb 23;38(8):2240-7. doi: 10.1021/bi982274t. Biochemistry. 1999. PMID: 10029516

8

The uncoupled state of the human formyl peptide receptor.

Gilbert TL, Prossnitz ER, Sklar LA. Gilbert TL, et al. Among authors: sklar la. J Recept Signal Transduct Res. 1999 Jan-Jul;19(1-4):327-40. doi: 10.3109/10799899909036655. J Recept Signal Transduct Res. 1999. PMID: 10071768

9

Real-time analysis of G protein-coupled receptor reconstitution in a solubilized system.

Bennett TA, Key TA, Gurevich VV, Neubig R, Prossnitz ER, Sklar LA. Bennett TA, et al. Among authors: sklar la. J Biol Chem. 2001 Jun 22;276(25):22453-60. doi: 10.1074/jbc.M009679200. Epub 2001 Apr 17. J Biol Chem. 2001. PMID: 11309376 Free article.

10

Regulation of formyl peptide receptor agonist affinity by reconstitution with arrestins and heterotrimeric G proteins.

Key TA, Bennett TA, Foutz TD, Gurevich VV, Sklar LA, Prossnitz ER. Key TA, et al. Among authors: sklar la. J Biol Chem. 2001 Dec 28;276(52):49204-12. doi: 10.1074/jbc.M109475200. Epub 2001 Oct 11. J Biol Chem. 2001. PMID: 11598142 Free article.

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