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Inhibition of Rho GTPases with protein prenyltransferase inhibitors prevents leukocyte recruitment to the central nervous system and attenuates clinical signs of disease in an animal model of multiple sclerosis.
Walters CE, Pryce G, Hankey DJR, Sebti SM, Hamilton AD, Baker D, Greenwood J, Adamson P. Walters CE, et al. Among authors: greenwood j. J Immunol. 2002 Apr 15;168(8):4087-4094. doi: 10.4049/jimmunol.168.8.4087. J Immunol. 2002. PMID: 11937568 Free PMC article.
How do statins control neuroinflammation?
Adamson P, Greenwood J. Adamson P, et al. Among authors: greenwood j. Inflamm Res. 2003 Oct;52(10):399-403. doi: 10.1007/s00011-003-1201-9. Inflamm Res. 2003. PMID: 14520514 Review.
1,401 results