Williams JI - Search Results

1

A Phase I and pharmacokinetic study of squalamine, an aminosterol angiogenesis inhibitor.

Hao D, Hammond LA, Eckhardt SG, Patnaik A, Takimoto CH, Schwartz GH, Goetz AD, Tolcher AW, McCreery HA, Mamun K, Williams JI, Holroyd KJ, Rowinsky EK. Hao D, et al. Among authors: williams ji. Clin Cancer Res. 2003 Jul;9(7):2465-71. Clin Cancer Res. 2003. PMID: 12855619 Clinical Trial.

2

A phase I/IIA trial of continuous five-day infusion of squalamine lactate (MSI-1256F) plus carboplatin and paclitaxel in patients with advanced non-small cell lung cancer.

Herbst RS, Hammond LA, Carbone DP, Tran HT, Holroyd KJ, Desai A, Williams JI, Bekele BN, Hait H, Allgood V, Solomon S, Schiller JH. Herbst RS, et al. Among authors: williams ji. Clin Cancer Res. 2003 Sep 15;9(11):4108-15. Clin Cancer Res. 2003. PMID: 14519633 Clinical Trial.

3

A phase I and pharmacokinetic study of squalamine, a novel antiangiogenic agent, in patients with advanced cancers.

Bhargava P, Marshall JL, Dahut W, Rizvi N, Trocky N, Williams JI, Hait H, Song S, Holroyd KJ, Hawkins MJ. Bhargava P, et al. Among authors: williams ji. Clin Cancer Res. 2001 Dec;7(12):3912-9. Clin Cancer Res. 2001. PMID: 11751482 Clinical Trial.

4

Squalamine lactate reduces choroidal neovascularization in a laser-injury model in the rat.

Ciulla TA, Criswell MH, Danis RP, Williams JI, McLane MP, Holroyd KJ. Ciulla TA, et al. Among authors: williams ji. Retina. 2003 Dec;23(6):808-14. doi: 10.1097/00006982-200312000-00011. Retina. 2003. PMID: 14707832

5

Squalamine treatment of human tumors in nu/nu mice enhances platinum-based chemotherapies.

Williams JI, Weitman S, Gonzalez CM, Jundt CH, Marty J, Stringer SD, Holroyd KJ, Mclane MP, Chen Q, Zasloff M, Von Hoff DD. Williams JI, et al. Clin Cancer Res. 2001 Mar;7(3):724-33. Clin Cancer Res. 2001. PMID: 11297269

6

Effect of squalamine on iris neovascularization in monkeys.

Genaidy M, Kazi AA, Peyman GA, Passos-Machado E, Farahat HG, Williams JI, Holroyd KJ, Blake DA. Genaidy M, et al. Among authors: williams ji. Retina. 2002 Dec;22(6):772-8. doi: 10.1097/00006982-200212000-00014. Retina. 2002. PMID: 12476105

7

Potential of the aminosterol, squalamine in combination therapy in the rat 13,762 mammary carcinoma and the murine Lewis lung carcinoma.

Teicher BA, Williams JI, Takeuchi H, Ara G, Herbst RS, Buxton D. Teicher BA, et al. Among authors: williams ji. Anticancer Res. 1998 Jul-Aug;18(4A):2567-73. Anticancer Res. 1998. PMID: 9703911

8

Squalamine and cisplatin block angiogenesis and growth of human ovarian cancer cells with or without HER-2 gene overexpression.

Li D, Williams JI, Pietras RJ. Li D, et al. Among authors: williams ji. Oncogene. 2002 Apr 25;21(18):2805-14. doi: 10.1038/sj.onc.1205410. Oncogene. 2002. PMID: 11973639

9

Regression of retinopathy by squalamine in a mouse model.

Higgins RD, Yan Y, Geng Y, Zasloff M, Williams JI. Higgins RD, et al. Among authors: williams ji. Pediatr Res. 2004 Jul;56(1):144-9. doi: 10.1203/01.PDR.0000128977.55799.34. Epub 2004 May 5. Pediatr Res. 2004. PMID: 15128931

10

Squalamine inhibits angiogenesis and solid tumor growth in vivo and perturbs embryonic vasculature.

Sills AK Jr, Williams JI, Tyler BM, Epstein DS, Sipos EP, Davis JD, McLane MP, Pitchford S, Cheshire K, Gannon FH, Kinney WA, Chao TL, Donowitz M, Laterra J, Zasloff M, Brem H. Sills AK Jr, et al. Among authors: williams ji. Cancer Res. 1998 Jul 1;58(13):2784-92. Cancer Res. 1998. PMID: 9661892

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