Hansen H - Search Results

1

The human anti-CD30 antibody 5F11 shows in vitro and in vivo activity against malignant lymphoma.

Borchmann P, Treml JF, Hansen H, Gottstein C, Schnell R, Staak O, Zhang HF, Davis T, Keler T, Diehl V, Graziano RF, Engert A. Borchmann P, et al. Among authors: hansen h. Blood. 2003 Nov 15;102(10):3737-42. doi: 10.1182/blood-2003-02-0515. Epub 2003 Jul 24. Blood. 2003. PMID: 12881320 Free article.

2

A Phase I study with an anti-CD30 ricin A-chain immunotoxin (Ki-4.dgA) in patients with refractory CD30+ Hodgkin's and non-Hodgkin's lymphoma.

Schnell R, Staak O, Borchmann P, Schwartz C, Matthey B, Hansen H, Schindler J, Ghetie V, Vitetta ES, Diehl V, Engert A. Schnell R, et al. Among authors: hansen h. Clin Cancer Res. 2002 Jun;8(6):1779-86. Clin Cancer Res. 2002. PMID: 12060617 Clinical Trial.

3

Combination of the human anti-CD30 antibody 5F11 with cytostatic drugs enhances its antitumor activity against Hodgkin and anaplastic large cell lymphoma cell lines.

Heuck F, Ellermann J, Borchmann P, Rothe A, Hansen H, Engert A, von Strandmann EP. Heuck F, et al. Among authors: hansen h. J Immunother. 2004 Sep-Oct;27(5):347-53. doi: 10.1097/00002371-200409000-00003. J Immunother. 2004. PMID: 15314543

4

The fully human anti-CD30 antibody 5F11 activates NF-{kappa}B and sensitizes lymphoma cells to bortezomib-induced apoptosis.

Böll B, Hansen H, Heuck F, Reiners K, Borchmann P, Rothe A, Engert A, Pogge von Strandmann E. Böll B, et al. Among authors: hansen h. Blood. 2005 Sep 1;106(5):1839-42. doi: 10.1182/blood-2005-01-0427. Epub 2005 May 5. Blood. 2005. PMID: 15878978 Free article.

5

Treatment of refractory Hodgkin's lymphoma patients with an iodine-131-labeled murine anti-CD30 monoclonal antibody.

Schnell R, Dietlein M, Staak JO, Borchmann P, Schomaecker K, Fischer T, Eschner W, Hansen H, Morschhauser F, Schicha H, Diehl V, Raubitschek A, Engert A. Schnell R, et al. Among authors: hansen h. J Clin Oncol. 2005 Jul 20;23(21):4669-78. doi: 10.1200/JCO.2005.09.098. J Clin Oncol. 2005. PMID: 16034043

6

Metalloproteinase inhibition augments antitumor efficacy of the anti-CD30 immunotoxin Ki-3(scFv)-ETA' against human lymphomas in vivo.

Matthey B, Borchmann P, Schnell R, Tawadros S, Lange H, Huhn M, Klimka A, Tur MK, Barth S, Engert A, Hansen HP. Matthey B, et al. Among authors: hansen hp. Int J Cancer. 2004 Sep 10;111(4):568-74. doi: 10.1002/ijc.20278. Int J Cancer. 2004. PMID: 15239135

7

A novel bispecific protein (ULBP2-BB4) targeting the NKG2D receptor on natural killer (NK) cells and CD138 activates NK cells and has potent antitumor activity against human multiple myeloma in vitro and in vivo.

von Strandmann EP, Hansen HP, Reiners KS, Schnell R, Borchmann P, Merkert S, Simhadri VR, Draube A, Reiser M, Purr I, Hallek M, Engert A. von Strandmann EP, et al. Blood. 2006 Mar 1;107(5):1955-62. doi: 10.1182/blood-2005-05-2177. Epub 2005 Oct 6. Blood. 2006. PMID: 16210338 Free article.

8

The ectodomain shedding of CD30 is specifically regulated by peptide motifs in its cysteine-rich domains 2 and 5.

Hansen HP, Recke A, Reineke U, Von Tresckow B, Borchmann P, Von Strandmann EP, Lange H, Lemke H, Engert A. Hansen HP, et al. FASEB J. 2004 May;18(7):893-5. doi: 10.1096/fj.03-0901fje. Epub 2004 Mar 19. FASEB J. 2004. PMID: 15033921

9

Depletion of cellular cholesterol and lipid rafts increases shedding of CD30.

von Tresckow B, Kallen KJ, von Strandmann EP, Borchmann P, Lange H, Engert A, Hansen HP. von Tresckow B, et al. Among authors: hansen hp. J Immunol. 2004 Apr 1;172(7):4324-31. doi: 10.4049/jimmunol.172.7.4324. J Immunol. 2004. PMID: 15034047

10

ADAM10 inhibition of human CD30 shedding increases specificity of targeted immunotherapy in vitro.

Eichenauer DA, Simhadri VL, von Strandmann EP, Ludwig A, Matthews V, Reiners KS, von Tresckow B, Saftig P, Rose-John S, Engert A, Hansen HP. Eichenauer DA, et al. Cancer Res. 2007 Jan 1;67(1):332-8. doi: 10.1158/0008-5472.CAN-06-2470. Cancer Res. 2007. PMID: 17210715

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