Cavener DR - Search Results

1

Phosphorylation of the alpha subunit of eukaryotic initiation factor 2 is required for activation of NF-kappaB in response to diverse cellular stresses.

Jiang HY, Wek SA, McGrath BC, Scheuner D, Kaufman RJ, Cavener DR, Wek RC. Jiang HY, et al. Among authors: cavener dr. Mol Cell Biol. 2003 Aug;23(16):5651-63. doi: 10.1128/MCB.23.16.5651-5663.2003. Mol Cell Biol. 2003. PMID: 12897138 Free PMC article.

2

The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas.

Zhang P, McGrath B, Li S, Frank A, Zambito F, Reinert J, Gannon M, Ma K, McNaughton K, Cavener DR. Zhang P, et al. Among authors: cavener dr. Mol Cell Biol. 2002 Jun;22(11):3864-74. doi: 10.1128/MCB.22.11.3864-3874.2002. Mol Cell Biol. 2002. PMID: 11997520 Free PMC article.

3

The GCN2 eIF2alpha kinase is required for adaptation to amino acid deprivation in mice.

Zhang P, McGrath BC, Reinert J, Olsen DS, Lei L, Gill S, Wek SA, Vattem KM, Wek RC, Kimball SR, Jefferson LS, Cavener DR. Zhang P, et al. Among authors: cavener dr. Mol Cell Biol. 2002 Oct;22(19):6681-8. doi: 10.1128/MCB.22.19.6681-6688.2002. Mol Cell Biol. 2002. PMID: 12215525 Free PMC article.

4

Activating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response.

Jiang HY, Wek SA, McGrath BC, Lu D, Hai T, Harding HP, Wang X, Ron D, Cavener DR, Wek RC. Jiang HY, et al. Among authors: cavener dr. Mol Cell Biol. 2004 Feb;24(3):1365-77. doi: 10.1128/MCB.24.3.1365-1377.2004. Mol Cell Biol. 2004. PMID: 14729979 Free PMC article.

5

Translational control and the unfolded protein response.

Wek RC, Cavener DR. Wek RC, et al. Among authors: cavener dr. Antioxid Redox Signal. 2007 Dec;9(12):2357-71. doi: 10.1089/ars.2007.1764. Antioxid Redox Signal. 2007. PMID: 17760508 Review.

6

A mammalian homologue of GCN2 protein kinase important for translational control by phosphorylation of eukaryotic initiation factor-2alpha.

Sood R, Porter AC, Olsen DA, Cavener DR, Wek RC. Sood R, et al. Among authors: cavener dr. Genetics. 2000 Feb;154(2):787-801. doi: 10.1093/genetics/154.2.787. Genetics. 2000. PMID: 10655230 Free PMC article.

7

Preservation of liver protein synthesis during dietary leucine deprivation occurs at the expense of skeletal muscle mass in mice deleted for eIF2 kinase GCN2.

Anthony TG, McDaniel BJ, Byerley RL, McGrath BC, Cavener DR, McNurlan MA, Wek RC. Anthony TG, et al. Among authors: cavener dr. J Biol Chem. 2004 Aug 27;279(35):36553-61. doi: 10.1074/jbc.M404559200. Epub 2004 Jun 22. J Biol Chem. 2004. PMID: 15213227 Free article.

8

GCN2 protein kinase is required to activate amino acid deprivation responses in mice treated with the anti-cancer agent L-asparaginase.

Bunpo P, Dudley A, Cundiff JK, Cavener DR, Wek RC, Anthony TG. Bunpo P, et al. Among authors: cavener dr. J Biol Chem. 2009 Nov 20;284(47):32742-9. doi: 10.1074/jbc.M109.047910. Epub 2009 Sep 25. J Biol Chem. 2009. PMID: 19783659 Free PMC article.

9

Uncharged tRNA and sensing of amino acid deficiency in mammalian piriform cortex.

Hao S, Sharp JW, Ross-Inta CM, McDaniel BJ, Anthony TG, Wek RC, Cavener DR, McGrath BC, Rudell JB, Koehnle TJ, Gietzen DW. Hao S, et al. Among authors: cavener dr. Science. 2005 Mar 18;307(5716):1776-8. doi: 10.1126/science.1104882. Science. 2005. PMID: 15774759

10

PERK (eIF2alpha kinase) is required to activate the stress-activated MAPKs and induce the expression of immediate-early genes upon disruption of ER calcium homoeostasis.

Liang SH, Zhang W, McGrath BC, Zhang P, Cavener DR. Liang SH, et al. Among authors: cavener dr. Biochem J. 2006 Jan 1;393(Pt 1):201-9. doi: 10.1042/BJ20050374. Biochem J. 2006. PMID: 16124869 Free PMC article.

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