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EDD, the human orthologue of the hyperplastic discs tumour suppressor gene, is amplified and overexpressed in cancer.
Clancy JL, Henderson MJ, Russell AJ, Anderson DW, Bova RJ, Campbell IG, Choong DY, Macdonald GA, Mann GJ, Nolan T, Brady G, Olopade OI, Woollatt E, Davies MJ, Segara D, Hacker NF, Henshall SM, Sutherland RL, Watts CK. Clancy JL, et al. Among authors: russell aj. Oncogene. 2003 Aug 7;22(32):5070-81. doi: 10.1038/sj.onc.1206775. Oncogene. 2003. PMID: 12902990
EDD mediates DNA damage-induced activation of CHK2.
Henderson MJ, Munoz MA, Saunders DN, Clancy JL, Russell AJ, Williams B, Pappin D, Khanna KK, Jackson SP, Sutherland RL, Watts CK. Henderson MJ, et al. Among authors: russell aj. J Biol Chem. 2006 Dec 29;281(52):39990-40000. doi: 10.1074/jbc.M602818200. Epub 2006 Oct 30. J Biol Chem. 2006. PMID: 17074762 Free article.
Modulation of myocardin function by the ubiquitin E3 ligase UBR5.
Hu G, Wang X, Saunders DN, Henderson M, Russell AJ, Herring BP, Zhou J. Hu G, et al. Among authors: russell aj. J Biol Chem. 2010 Apr 16;285(16):11800-9. doi: 10.1074/jbc.M109.079384. Epub 2010 Feb 18. J Biol Chem. 2010. PMID: 20167605 Free PMC article.
A Myc Activity Signature Predicts Poor Clinical Outcomes in Myc-Associated Cancers.
Jung M, Russell AJ, Liu B, George J, Liu PY, Liu T, DeFazio A, Bowtell DD, Oberthuer A, London WB, Fletcher JI, Haber M, Norris MD, Henderson MJ. Jung M, et al. Among authors: russell aj. Cancer Res. 2017 Feb 15;77(4):971-981. doi: 10.1158/0008-5472.CAN-15-2906. Epub 2016 Dec 6. Cancer Res. 2017. PMID: 27923830
Clinical Importance of Myc Family Oncogene Aberrations in Epithelial Ovarian Cancer.
Jung M, Russell AJ, Kennedy C, Gifford AJ; Australian Ovarian Cancer Study Group; Mallitt KA, Sivarajasingam S, Bowtell DD, DeFazio A, Haber M, Norris MD, Henderson MJ. Jung M, et al. Among authors: russell aj. JNCI Cancer Spectr. 2018 Nov 16;2(3):pky047. doi: 10.1093/jncics/pky047. eCollection 2018 Jul. JNCI Cancer Spectr. 2018. PMID: 31360864 Free PMC article.
420 results