Sotillo R - Search Results

1

Genetic rescue of Cdk4 null mice restores pancreatic beta-cell proliferation but not homeostatic cell number.

Martín J, Hunt SL, Dubus P, Sotillo R, Néhmé-Pélluard F, Magnuson MA, Parlow AF, Malumbres M, Ortega S, Barbacid M. Martín J, et al. Among authors: sotillo r. Oncogene. 2003 Aug 14;22(34):5261-9. doi: 10.1038/sj.onc.1206506. Oncogene. 2003. PMID: 12917627

2

Driving the cell cycle to cancer.

Malumbres M, Hunt SL, Sotillo R, Martín J, Odajima J, Martín A, Dubus P, Ortega S, Barbacid M. Malumbres M, et al. Among authors: sotillo r. Adv Exp Med Biol. 2003;532:1-11. doi: 10.1007/978-1-4615-0081-0_1. Adv Exp Med Biol. 2003. PMID: 12908544 Review.

3

Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6.

Malumbres M, Sotillo R, Santamaría D, Galán J, Cerezo A, Ortega S, Dubus P, Barbacid M. Malumbres M, et al. Among authors: sotillo r. Cell. 2004 Aug 20;118(4):493-504. doi: 10.1016/j.cell.2004.08.002. Cell. 2004. PMID: 15315761 Free article.

4

Cooperation between Cdk4 and p27kip1 in tumor development: a preclinical model to evaluate cell cycle inhibitors with therapeutic activity.

Sotillo R, Renner O, Dubus P, Ruiz-Cabello J, Martín-Caballero J, Barbacid M, Carnero A, Malumbres M. Sotillo R, et al. Cancer Res. 2005 May 1;65(9):3846-52. doi: 10.1158/0008-5472.CAN-04-4195. Cancer Res. 2005. PMID: 15867383

5

Invasive melanoma in Cdk4-targeted mice.

Sotillo R, García JF, Ortega S, Martin J, Dubus P, Barbacid M, Malumbres M. Sotillo R, et al. Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):13312-7. doi: 10.1073/pnas.241338598. Epub 2001 Oct 23. Proc Natl Acad Sci U S A. 2001. PMID: 11606789 Free PMC article.

6

Wide spectrum of tumors in knock-in mice carrying a Cdk4 protein insensitive to INK4 inhibitors.

Sotillo R, Dubus P, Martín J, de la Cueva E, Ortega S, Malumbres M, Barbacid M. Sotillo R, et al. EMBO J. 2001 Dec 3;20(23):6637-47. doi: 10.1093/emboj/20.23.6637. EMBO J. 2001. PMID: 11726500 Free PMC article.

7

Cell cycle and cancer: genetic analysis of the role of cyclin-dependent kinases.

Barbacid M, Ortega S, Sotillo R, Odajima J, Martín A, Santamaría D, Dubus P, Malumbres M. Barbacid M, et al. Among authors: sotillo r. Cold Spring Harb Symp Quant Biol. 2005;70:233-40. doi: 10.1101/sqb.2005.70.005. Cold Spring Harb Symp Quant Biol. 2005. PMID: 16869759

8

Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice.

Ortega S, Prieto I, Odajima J, Martín A, Dubus P, Sotillo R, Barbero JL, Malumbres M, Barbacid M. Ortega S, et al. Among authors: sotillo r. Nat Genet. 2003 Sep;35(1):25-31. doi: 10.1038/ng1232. Epub 2003 Aug 17. Nat Genet. 2003. PMID: 12923533

9

Limited overlapping roles of P15(INK4b) and P18(INK4c) cell cycle inhibitors in proliferation and tumorigenesis.

Latres E, Malumbres M, Sotillo R, Martín J, Ortega S, Martín-Caballero J, Flores JM, Cordón-Cardo C, Barbacid M. Latres E, et al. Among authors: sotillo r. EMBO J. 2000 Jul 3;19(13):3496-506. doi: 10.1093/emboj/19.13.3496. EMBO J. 2000. PMID: 10880462 Free PMC article.

10

Plk1 overexpression induces chromosomal instability and suppresses tumor development.

de Cárcer G, Venkateswaran SV, Salgueiro L, El Bakkali A, Somogyi K, Rowald K, Montañés P, Sanclemente M, Escobar B, de Martino A, McGranahan N, Malumbres M, Sotillo R. de Cárcer G, et al. Among authors: sotillo r. Nat Commun. 2018 Aug 1;9(1):3012. doi: 10.1038/s41467-018-05429-5. Nat Commun. 2018. PMID: 30069007 Free PMC article.

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