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Page 1
The kinetics of binding to p38MAP kinase by analogues of BIRB 796.
Regan J, Pargellis CA, Cirillo PF, Gilmore T, Hickey ER, Peet GW, Proto A, Swinamer A, Moss N. Regan J, et al. Among authors: peet gw. Bioorg Med Chem Lett. 2003 Sep 15;13(18):3101-4. doi: 10.1016/s0960-894x(03)00656-5. Bioorg Med Chem Lett. 2003. PMID: 12941343
Optimization of 2-phenylaminoimidazo[4,5-h]isoquinolin-9-ones: orally active inhibitors of lck kinase.
Goldberg DR, Butz T, Cardozo MG, Eckner RJ, Hammach A, Huang J, Jakes S, Kapadia S, Kashem M, Lukas S, Morwick TM, Panzenbeck M, Patel U, Pav S, Peet GW, Peterson JD, Prokopowicz AS 3rd, Snow RJ, Sellati R, Takahashi H, Tan J, Tschantz MA, Wang XJ, Wang Y, Wolak J, Xiong P, Moss N. Goldberg DR, et al. Among authors: peet gw. J Med Chem. 2003 Apr 10;46(8):1337-49. doi: 10.1021/jm020446l. J Med Chem. 2003. PMID: 12672234
Catalysis and function of the p38 alpha.MK2a signaling complex.
Lukas SM, Kroe RR, Wildeson J, Peet GW, Frego L, Davidson W, Ingraham RH, Pargellis CA, Labadia ME, Werneburg BG. Lukas SM, et al. Among authors: peet gw. Biochemistry. 2004 Aug 10;43(31):9950-60. doi: 10.1021/bi049508v. Biochemistry. 2004. PMID: 15287722
The discovery of carboline analogs as potent MAPKAP-K2 inhibitors.
Wu JP, Wang J, Abeywardane A, Andersen D, Emmanuel M, Gautschi E, Goldberg DR, Kashem MA, Lukas S, Mao W, Martin L, Morwick T, Moss N, Pargellis C, Patel UR, Patnaude L, Peet GW, Skow D, Snow RJ, Ward Y, Werneburg B, White A. Wu JP, et al. Among authors: peet gw. Bioorg Med Chem Lett. 2007 Aug 15;17(16):4664-9. doi: 10.1016/j.bmcl.2007.05.101. Epub 2007 Jun 7. Bioorg Med Chem Lett. 2007. PMID: 17576063
Inhibition of pro-inflammatory cytokine production by the dual p38/JNK2 inhibitor BIRB796 correlates with the inhibition of p38 signaling.
Gruenbaum LM, Schwartz R, Woska JR Jr, DeLeon RP, Peet GW, Warren TC, Capolino A, Mara L, Morelock MM, Shrutkowski A, Jones JW, Pargellis CA. Gruenbaum LM, et al. Among authors: peet gw. Biochem Pharmacol. 2009 Feb 1;77(3):422-32. doi: 10.1016/j.bcp.2008.10.032. Epub 2008 Nov 5. Biochem Pharmacol. 2009. PMID: 19027720
The discovery of thienopyridine analogues as potent IkappaB kinase beta inhibitors. Part II.
Wu JP, Fleck R, Brickwood J, Capolino A, Catron K, Chen Z, Cywin C, Emeigh J, Foerst M, Ginn J, Hrapchak M, Hickey E, Hao MH, Kashem M, Li J, Liu W, Morwick T, Nelson R, Marshall D, Martin L, Nemoto P, Potocki I, Liuzzi M, Peet GW, Scouten E, Stefany D, Turner M, Weldon S, Zimmitti C, Spero D, Kelly TA. Wu JP, et al. Among authors: peet gw. Bioorg Med Chem Lett. 2009 Oct 1;19(19):5547-51. doi: 10.1016/j.bmcl.2009.08.054. Epub 2009 Aug 15. Bioorg Med Chem Lett. 2009. PMID: 19716697
18 results