Khuri F - Search Results

1

Implication of protein kinase B/Akt and Bcl-2/Bcl-XL suppression by the farnesyl transferase inhibitor SCH66336 in apoptosis induction in squamous carcinoma cells.

Chun KH, Lee HY, Hassan K, Khuri F, Hong WK, Lotan R. Chun KH, et al. Among authors: khuri f. Cancer Res. 2003 Aug 15;63(16):4796-800. Cancer Res. 2003. PMID: 12941797

2

Phase II study of induction chemotherapy with paclitaxel, ifosfamide, and carboplatin (TIC) for patients with locally advanced squamous cell carcinoma of the head and neck.

Shin DM, Glisson BS, Khuri FR, Lippman SM, Ginsberg L, Diaz E Jr, Papadimitrakopoulou V, Feng L, Francisco M, Garden A, Kies MS, Myers J, Clayman G, Hong WK. Shin DM, et al. Cancer. 2002 Jul 15;95(2):322-30. doi: 10.1002/cncr.10661. Cancer. 2002. PMID: 12124833 Free article. Clinical Trial.

3

Effects of insulin-like growth factor binding protein-3 and farnesyltransferase inhibitor SCH66336 on Akt expression and apoptosis in non-small-cell lung cancer cells.

Lee HY, Moon H, Chun KH, Chang YS, Hassan K, Ji L, Lotan R, Khuri FR, Hong WK. Lee HY, et al. J Natl Cancer Inst. 2004 Oct 20;96(20):1536-48. doi: 10.1093/jnci/djh286. J Natl Cancer Inst. 2004. PMID: 15494604

4

Insulin-like growth factor-I receptor signaling pathway induces resistance to the apoptotic activities of SCH66336 (lonafarnib) through Akt/mammalian target of rapamycin-mediated increases in survivin expression.

Oh SH, Jin Q, Kim ES, Khuri FR, Lee HY. Oh SH, et al. Clin Cancer Res. 2008 Mar 1;14(5):1581-9. doi: 10.1158/1078-0432.CCR-07-0952. Clin Cancer Res. 2008. PMID: 18316583

5

Novel susceptibility loci for second primary tumors/recurrence in head and neck cancer patients: large-scale evaluation of genetic variants.

Wu X, Spitz MR, Lee JJ, Lippman SM, Ye Y, Yang H, Khuri FR, Kim E, Gu J, Lotan R, Hong WK. Wu X, et al. Cancer Prev Res (Phila). 2009 Jul;2(7):617-24. doi: 10.1158/1940-6207.CAPR-09-0025. Cancer Prev Res (Phila). 2009. PMID: 19584075 Free PMC article.

6

Genetic variants in the PI3K/PTEN/AKT/mTOR pathway predict head and neck cancer patient second primary tumor/recurrence risk and response to retinoid chemoprevention.

Hildebrandt MA, Lippman SM, Etzel CJ, Kim E, Lee JJ, Khuri FR, Spitz MR, Lotan R, Hong WK, Wu X. Hildebrandt MA, et al. Clin Cancer Res. 2012 Jul 1;18(13):3705-13. doi: 10.1158/1078-0432.CCR-11-3271. Epub 2012 May 10. Clin Cancer Res. 2012. PMID: 22577058 Free PMC article.

7

Overexpression of cyclin B1 in early-stage non-small cell lung cancer and its clinical implication.

Soria JC, Jang SJ, Khuri FR, Hassan K, Liu D, Hong WK, Mao L. Soria JC, et al. Among authors: khuri fr. Cancer Res. 2000 Aug 1;60(15):4000-4. Cancer Res. 2000. PMID: 10945597

8

Identification of insulin-like growth factor binding protein-3 as a farnesyl transferase inhibitor SCH66336-induced negative regulator of angiogenesis in head and neck squamous cell carcinoma.

Oh SH, Kim WY, Kim JH, Younes MN, El-Naggar AK, Myers JN, Kies M, Cohen P, Khuri F, Hong WK, Lee HY. Oh SH, et al. Among authors: khuri f. Clin Cancer Res. 2006 Jan 15;12(2):653-61. doi: 10.1158/1078-0432.CCR-05-1725. Clin Cancer Res. 2006. PMID: 16428512

9

Phase II and biologic study of interferon alfa, retinoic acid, and cisplatin in advanced squamous skin cancer.

Shin DM, Glisson BS, Khuri FR, Clifford JL, Clayman G, Benner SE, Forastiere AA, Ginsberg L, Liu D, Lee JJ, Myers J, Goepfert H, Lotan R, Hong WK, Lippman SM. Shin DM, et al. J Clin Oncol. 2002 Jan 15;20(2):364-70. doi: 10.1200/JCO.2002.20.2.364. J Clin Oncol. 2002. PMID: 11786562 Clinical Trial.

10

Lack of PTEN expression in non-small cell lung cancer could be related to promoter methylation.

Soria JC, Lee HY, Lee JI, Wang L, Issa JP, Kemp BL, Liu DD, Kurie JM, Mao L, Khuri FR. Soria JC, et al. Clin Cancer Res. 2002 May;8(5):1178-84. Clin Cancer Res. 2002. PMID: 12006535

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