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Overexpression of nicastrin increases Abeta production.
Murphy MP, Das P, Nyborg AC, Rochette MJ, Dodson MW, Loosbrock NM, Souder TM, McLendon C, Merit SL, Piper SC, Jansen KR, Golde TE. Murphy MP, et al. Among authors: loosbrock nm. FASEB J. 2003 Jun;17(9):1138-40. doi: 10.1096/fj.02-1050fje. Epub 2003 Apr 8. FASEB J. 2003. PMID: 12692078