Denny WA - Search Results

1

5-Nitro-4-(N,N-dimethylaminopropylamino)quinoline (5-nitraquine), a new DNA-affinic hypoxic cell radiosensitizer and bioreductive agent: comparison with nitracrine.

Wilson WR, Siim BG, Denny WA, van Zijl PL, Taylor ML, Chambers DM, Roberts PB. Wilson WR, et al. Among authors: denny wa. Radiat Res. 1992 Sep;131(3):257-65. Radiat Res. 1992. PMID: 1438685

2

Optimization of the auxiliary ligand shell of Cobalt(III)(8-hydroxyquinoline) complexes as model hypoxia-selective radiation-activated prodrugs.

Ahn GO, Ware DC, Denny WA, Wilson WR. Ahn GO, et al. Among authors: denny wa. Radiat Res. 2004 Sep;162(3):315-25. doi: 10.1667/rr3229. Radiat Res. 2004. PMID: 15333003

3

Hypoxia-selective antitumor agents. 6. 4-(Alkylamino)nitroquinolines: a new class of hypoxia-selective cytotoxins.

Denny WA, Atwell GJ, Roberts PB, Anderson RF, Boyd M, Lock CJ, Wilson WR. Denny WA, et al. J Med Chem. 1992 Dec 25;35(26):4832-41. doi: 10.1021/jm00104a008. J Med Chem. 1992. PMID: 1479583

4

Bis-bioreductive agents as hypoxia-selective cytotoxins: nitracrine N-oxide.

Wilson WR, Van Zijl P, Denny WA. Wilson WR, et al. Among authors: denny wa. Int J Radiat Oncol Biol Phys. 1992;22(4):693-6. doi: 10.1016/0360-3016(92)90505-c. Int J Radiat Oncol Biol Phys. 1992. PMID: 1544839

5

NLA-1: a 2-nitroimidazole radiosensitizer targeted to DNA by intercalation.

Denny WA, Roberts PB, Anderson RF, Brown JM, Phil D, Wilson WR. Denny WA, et al. Int J Radiat Oncol Biol Phys. 1992;22(3):553-6. doi: 10.1016/0360-3016(92)90874-h. Int J Radiat Oncol Biol Phys. 1992. PMID: 1735695

6

Radiosensitization of mammalian cells in vitro by nitroacridines.

Roberts PB, Denny WA, Wakelin LP, Anderson RF, Wilson WR. Roberts PB, et al. Among authors: denny wa. Radiat Res. 1990 Aug;123(2):153-64. Radiat Res. 1990. PMID: 2389001

7

Hypoxia-selective antitumor agents. 1. Relationships between structure, redox properties and hypoxia-selective cytotoxicity for 4-substituted derivatives of nitracrine.

Wilson WR, Anderson RF, Denny WA. Wilson WR, et al. Among authors: denny wa. J Med Chem. 1989 Jan;32(1):23-30. doi: 10.1021/jm00121a006. J Med Chem. 1989. PMID: 2909736

8

Hypoxia-selective antitumor agents. 2. Electronic effects of 4-substituents on the mechanisms of cytotoxicity and metabolic stability of nitracrine derivatives.

Wilson WR, Thompson LH, Anderson RF, Denny WA. Wilson WR, et al. Among authors: denny wa. J Med Chem. 1989 Jan;32(1):31-8. doi: 10.1021/jm00121a007. J Med Chem. 1989. PMID: 2909741

9

Hypoxia-selective antitumor agents. 10. bis(nitroimidazoles) and related Bis(nitroheterocycles): development of derivatives with higher rates of metabolic activation under hypoxia and improved aqueous solubility.

Hay MP, Lee HH, Wilson WR, Roberts PB, Denny WA. Hay MP, et al. Among authors: denny wa. J Med Chem. 1995 May 26;38(11):1928-41. doi: 10.1021/jm00011a013. J Med Chem. 1995. PMID: 7783125

10

N-[2-(2-methyl-5-nitroimidazolyl)ethyl]-4-(2-nitroimidazolyl)butanamide (NSC 639862), a bisnitroimidazole with enhanced selectivity as a bioreductive drug.

Moselen JW, Hay MP, Denny WA, Wilson WR. Moselen JW, et al. Among authors: denny wa. Cancer Res. 1995 Feb 1;55(3):574-80. Cancer Res. 1995. PMID: 7834627

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