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Cell-mediated cleavage of Pseudomonas exotoxin between Arg279 and Gly280 generates the enzymatically active fragment which translocates to the cytosol.
Ogata M, Fryling CM, Pastan I, FitzGerald DJ. Ogata M, et al. J Biol Chem. 1992 Dec 15;267(35):25396-401. J Biol Chem. 1992. PMID: 1460035 Free article.
Pseudomonas exotoxin (PE) is a three-domain toxin which is cleaved by a cellular protease within cells and then reduced to generate two prominent fragments (Ogata, M., Chaudhary, V. K., Pastan, I., and FitzGerald, D. J. (1990) J. Biol. Chem. 265, 20678-20685). ...
Pseudomonas exotoxin (PE) is a three-domain toxin which is cleaved by a cellular protease within cells and then reduced to generate two prom …
Characterization of a cellular protease that cleaves Pseudomonas exotoxin.
Fryling C, Ogata M, FitzGerald D. Fryling C, et al. Among authors: ogata m. Infect Immun. 1992 Feb;60(2):497-502. doi: 10.1128/iai.60.2.497-502.1992. Infect Immun. 1992. PMID: 1730481 Free PMC article.
Pseudomonas exotoxin (PE) is a 66-kDa bacterial toxin that is proteolytically cleaved by cells to produce an N-terminal fragment of 28 kDa and a C-terminal 37-kDa fragment which translocates to the cytosol and inhibits protein synthesis (M. Ogata, V.K. Chaudhary, I. …
Pseudomonas exotoxin (PE) is a 66-kDa bacterial toxin that is proteolytically cleaved by cells to produce an N-terminal fragment of 28 kDa a …
Cardiac allograft survival in mice treated with IL-2-PE40.
Lorberboum-Galski H, Barrett LV, Kirkman RL, Ogata M, Willingham MC, FitzGerald DJ, Pastan I. Lorberboum-Galski H, et al. Among authors: ogata m. Proc Natl Acad Sci U S A. 1989 Feb;86(3):1008-12. doi: 10.1073/pnas.86.3.1008. Proc Natl Acad Sci U S A. 1989. PMID: 2644640 Free PMC article.
1,501 results