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Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression.
de Waal Malefyt R, Haanen J, Spits H, Roncarolo MG, te Velde A, Figdor C, Johnson K, Kastelein R, Yssel H, de Vries JE. de Waal Malefyt R, et al. J Exp Med. 1991 Oct 1;174(4):915-24. doi: 10.1084/jem.174.4.915. J Exp Med. 1991. PMID: 1655948 Free PMC article.
141 results