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Page 1
Small-intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency.
Jackson RS, Creemers JW, Farooqi IS, Raffin-Sanson ML, Varro A, Dockray GJ, Holst JJ, Brubaker PL, Corvol P, Polonsky KS, Ostrega D, Becker KL, Bertagna X, Hutton JC, White A, Dattani MT, Hussain K, Middleton SJ, Nicole TM, Milla PJ, Lindley KJ, O'Rahilly S. Jackson RS, et al. Among authors: creemers jw. J Clin Invest. 2003 Nov;112(10):1550-60. doi: 10.1172/JCI18784. J Clin Invest. 2003. PMID: 14617756 Free PMC article.
A missense mutation disrupting a dibasic prohormone processing site in pro-opiomelanocortin (POMC) increases susceptibility to early-onset obesity through a novel molecular mechanism.
Challis BG, Pritchard LE, Creemers JW, Delplanque J, Keogh JM, Luan J, Wareham NJ, Yeo GS, Bhattacharyya S, Froguel P, White A, Farooqi IS, O'Rahilly S. Challis BG, et al. Among authors: creemers jw. Hum Mol Genet. 2002 Aug 15;11(17):1997-2004. doi: 10.1093/hmg/11.17.1997. Hum Mol Genet. 2002. PMID: 12165561
Proprotein processing and pancreatic islet function.
Hutton J, Wasmeier C, Amaria R, Bright N, Creemers J. Hutton J, et al. Adv Exp Med Biol. 2004;552:39-65. Adv Exp Med Biol. 2004. PMID: 15622958 Review. No abstract available.
Proprotein convertase furin regulates osteocalcin and bone endocrine function.
Al Rifai O, Chow J, Lacombe J, Julien C, Faubert D, Susan-Resiga D, Essalmani R, Creemers JW, Seidah NG, Ferron M. Al Rifai O, et al. Among authors: creemers jw. J Clin Invest. 2017 Nov 1;127(11):4104-4117. doi: 10.1172/JCI93437. Epub 2017 Oct 3. J Clin Invest. 2017. PMID: 28972540 Free PMC article.
148 results