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New antibacterial tetrahydro-4(2H)-thiopyran and thiomorpholine S-oxide and S,S-dioxide phenyloxazolidinones.
Singh U, Raju B, Lam S, Zhou J, Gadwood RC, Ford CW, Zurenko GE, Schaadt RD, Morin SE, Adams WJ, Friis JM, Courtney M, Palandra J, Hackbarth CJ, Lopez S, Wu C, Mortell KH, Trias J, Yuan Z, Patel DV, Gordeev MF. Singh U, et al. Among authors: lopez s. Bioorg Med Chem Lett. 2003 Dec 1;13(23):4209-12. doi: 10.1016/j.bmcl.2003.07.022. Bioorg Med Chem Lett. 2003. PMID: 14623003
Novel antibacterial azetidine lincosamides.
O'Dowd H, Lewis JG, Trias J, Asano R, Blais J, Lopez SL, Park CK, Wu C, Wang W, Gordeev MF. O'Dowd H, et al. Bioorg Med Chem Lett. 2008 Apr 15;18(8):2645-8. doi: 10.1016/j.bmcl.2008.03.032. Epub 2008 Mar 14. Bioorg Med Chem Lett. 2008. PMID: 18359228
N-alkyl urea hydroxamic acids as a new class of peptide deformylase inhibitors with antibacterial activity.
Hackbarth CJ, Chen DZ, Lewis JG, Clark K, Mangold JB, Cramer JA, Margolis PS, Wang W, Koehn J, Wu C, Lopez S, Withers G 3rd, Gu H, Dunn E, Kulathila R, Pan SH, Porter WL, Jacobs J, Trias J, Patel DV, Weidmann B, White RJ, Yuan Z. Hackbarth CJ, et al. Among authors: lopez s. Antimicrob Agents Chemother. 2002 Sep;46(9):2752-64. doi: 10.1128/AAC.46.9.2752-2764.2002. Antimicrob Agents Chemother. 2002. PMID: 12183225 Free PMC article.
Optimization of novel monobactams with activity against carbapenem-resistant Enterobacteriaceae - Identification of LYS228.
Reck F, Bermingham A, Blais J, Capka V, Cariaga T, Casarez A, Colvin R, Dean CR, Fekete A, Gong W, Growcott E, Guo H, Jones AK, Li C, Li F, Lin X, Lindvall M, Lopez S, McKenney D, Metzger L, Moser HE, Prathapam R, Rasper D, Rudewicz P, Sethuraman V, Shen X, Shaul J, Simmons RL, Tashiro K, Tang D, Tjandra M, Turner N, Uehara T, Vitt C, Whitebread S, Yifru A, Zang X, Zhu Q. Reck F, et al. Among authors: lopez s. Bioorg Med Chem Lett. 2018 Feb 15;28(4):748-755. doi: 10.1016/j.bmcl.2018.01.006. Epub 2018 Jan 4. Bioorg Med Chem Lett. 2018. PMID: 29336873
Synthesis and spectrum of the neoglycoside ACHN-490.
Aggen JB, Armstrong ES, Goldblum AA, Dozzo P, Linsell MS, Gliedt MJ, Hildebrandt DJ, Feeney LA, Kubo A, Matias RD, Lopez S, Gomez M, Wlasichuk KB, Diokno R, Miller GH, Moser HE. Aggen JB, et al. Among authors: lopez s. Antimicrob Agents Chemother. 2010 Nov;54(11):4636-42. doi: 10.1128/AAC.00572-10. Epub 2010 Aug 30. Antimicrob Agents Chemother. 2010. PMID: 20805391 Free PMC article.
2,195 results