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New antibacterial tetrahydro-4(2H)-thiopyran and thiomorpholine S-oxide and S,S-dioxide phenyloxazolidinones.
Singh U, Raju B, Lam S, Zhou J, Gadwood RC, Ford CW, Zurenko GE, Schaadt RD, Morin SE, Adams WJ, Friis JM, Courtney M, Palandra J, Hackbarth CJ, Lopez S, Wu C, Mortell KH, Trias J, Yuan Z, Patel DV, Gordeev MF. Singh U, et al. Among authors: yuan z. Bioorg Med Chem Lett. 2003 Dec 1;13(23):4209-12. doi: 10.1016/j.bmcl.2003.07.022. Bioorg Med Chem Lett. 2003. PMID: 14623003
N- and C-terminal modifications of negamycin.
Raju B, Mortell K, Anandan S, O'Dowd H, Gao H, Gomez M, Hackbarth C, Wu C, Wang W, Yuan Z, White R, Trias J, Patel DV. Raju B, et al. Among authors: yuan z. Bioorg Med Chem Lett. 2003 Jul 21;13(14):2413-8. doi: 10.1016/s0960-894x(03)00393-7. Bioorg Med Chem Lett. 2003. PMID: 12824046
Conformationally restricted analogs of deoxynegamycin.
Raju B, Anandan S, Gu S, Herradura P, O'Dowd H, Kim B, Gomez M, Hackbarth C, Wu C, Wang W, Yuan Z, White R, Trias J, Patel DV. Raju B, et al. Among authors: yuan z. Bioorg Med Chem Lett. 2004 Jun 21;14(12):3103-7. doi: 10.1016/j.bmcl.2004.04.036. Bioorg Med Chem Lett. 2004. PMID: 15149653
N-alkyl urea hydroxamic acids as a new class of peptide deformylase inhibitors with antibacterial activity.
Hackbarth CJ, Chen DZ, Lewis JG, Clark K, Mangold JB, Cramer JA, Margolis PS, Wang W, Koehn J, Wu C, Lopez S, Withers G 3rd, Gu H, Dunn E, Kulathila R, Pan SH, Porter WL, Jacobs J, Trias J, Patel DV, Weidmann B, White RJ, Yuan Z. Hackbarth CJ, et al. Among authors: yuan z. Antimicrob Agents Chemother. 2002 Sep;46(9):2752-64. doi: 10.1128/AAC.46.9.2752-2764.2002. Antimicrob Agents Chemother. 2002. PMID: 12183225 Free PMC article.
Peptide deformylase inhibitors as antibacterial agents: identification of VRC3375, a proline-3-alkylsuccinyl hydroxamate derivative, by using an integrated combinatorial and medicinal chemistry approach.
Chen D, Hackbarth C, Ni ZJ, Wu C, Wang W, Jain R, He Y, Bracken K, Weidmann B, Patel DV, Trias J, White RJ, Yuan Z. Chen D, et al. Among authors: yuan z. Antimicrob Agents Chemother. 2004 Jan;48(1):250-61. doi: 10.1128/AAC.48.1.250-261.2004. Antimicrob Agents Chemother. 2004. PMID: 14693547 Free PMC article.
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