Richardson A - Search Results

1

Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging.

Van Remmen H, Ikeno Y, Hamilton M, Pahlavani M, Wolf N, Thorpe SR, Alderson NL, Baynes JW, Epstein CJ, Huang TT, Nelson J, Strong R, Richardson A. Van Remmen H, et al. Among authors: richardson a. Physiol Genomics. 2003 Dec 16;16(1):29-37. doi: 10.1152/physiolgenomics.00122.2003. Physiol Genomics. 2003. PMID: 14679299

2

Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress.

Van Remmen H, Qi W, Sabia M, Freeman G, Estlack L, Yang H, Mao Guo Z, Huang TT, Strong R, Lee S, Epstein CJ, Richardson A. Van Remmen H, et al. Among authors: richardson a. Free Radic Biol Med. 2004 Jun 15;36(12):1625-34. doi: 10.1016/j.freeradbiomed.2004.03.016. Free Radic Biol Med. 2004. PMID: 15182862

3

Alterations in mitochondrial function, hydrogen peroxide release and oxidative damage in mouse hind-limb skeletal muscle during aging.

Mansouri A, Muller FL, Liu Y, Ng R, Faulkner J, Hamilton M, Richardson A, Huang TT, Epstein CJ, Van Remmen H. Mansouri A, et al. Among authors: richardson a. Mech Ageing Dev. 2006 Mar;127(3):298-306. doi: 10.1016/j.mad.2005.11.004. Epub 2006 Jan 6. Mech Ageing Dev. 2006. PMID: 16405961

4

Reduction in glutathione peroxidase 4 increases life span through increased sensitivity to apoptosis.

Ran Q, Liang H, Ikeno Y, Qi W, Prolla TA, Roberts LJ 2nd, Wolf N, Van Remmen H, Richardson A. Ran Q, et al. Among authors: richardson a. J Gerontol A Biol Sci Med Sci. 2007 Sep;62(9):932-42. doi: 10.1093/gerona/62.9.932. J Gerontol A Biol Sci Med Sci. 2007. PMID: 17895430

5

Mice deficient in both Mn superoxide dismutase and glutathione peroxidase-1 have increased oxidative damage and a greater incidence of pathology but no reduction in longevity.

Zhang Y, Ikeno Y, Qi W, Chaudhuri A, Li Y, Bokov A, Thorpe SR, Baynes JW, Epstein C, Richardson A, Van Remmen H. Zhang Y, et al. Among authors: richardson a. J Gerontol A Biol Sci Med Sci. 2009 Dec;64(12):1212-20. doi: 10.1093/gerona/glp132. Epub 2009 Sep 23. J Gerontol A Biol Sci Med Sci. 2009. PMID: 19776219 Free PMC article.

6

Increased oxidative damage is correlated to altered mitochondrial function in heterozygous manganese superoxide dismutase knockout mice.

Williams MD, Van Remmen H, Conrad CC, Huang TT, Epstein CJ, Richardson A. Williams MD, et al. Among authors: richardson a. J Biol Chem. 1998 Oct 23;273(43):28510-5. doi: 10.1074/jbc.273.43.28510. J Biol Chem. 1998. PMID: 9774481 Free article.

7

Oxidative damage to mitochondria and aging.

Van Remmen H, Richardson A. Van Remmen H, et al. Among authors: richardson a. Exp Gerontol. 2001 Jul;36(7):957-68. doi: 10.1016/s0531-5565(01)00093-6. Exp Gerontol. 2001. PMID: 11404044 Review.

8

Oxidative damage to DNA and aging.

Van Remmen H, Hamilton ML, Richardson A. Van Remmen H, et al. Among authors: richardson a. Exerc Sport Sci Rev. 2003 Jul;31(3):149-53. doi: 10.1097/00003677-200307000-00009. Exerc Sport Sci Rev. 2003. PMID: 12882482 Review.

9

Does oxidative damage to DNA increase with age?

Hamilton ML, Van Remmen H, Drake JA, Yang H, Guo ZM, Kewitt K, Walter CA, Richardson A. Hamilton ML, et al. Among authors: richardson a. Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10469-74. doi: 10.1073/pnas.171202698. Epub 2001 Aug 21. Proc Natl Acad Sci U S A. 2001. PMID: 11517304 Free PMC article.

10

A strategy for the ubiquitous overexpression of human catalase and CuZn superoxide dismutase genes in transgenic mice.

Chen X, Mele J, Giese H, Van Remmen H, Dollé ME, Steinhelper M, Richardson A, Vijg J. Chen X, et al. Among authors: richardson a. Mech Ageing Dev. 2003 Feb;124(2):219-27. doi: 10.1016/s0047-6374(02)00161-6. Mech Ageing Dev. 2003. PMID: 12633942

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