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Pten dose dictates cancer progression in the prostate.
Trotman LC, Niki M, Dotan ZA, Koutcher JA, Di Cristofano A, Xiao A, Khoo AS, Roy-Burman P, Greenberg NM, Van Dyke T, Cordon-Cardo C, Pandolfi PP. Trotman LC, et al. Among authors: koutcher ja. PLoS Biol. 2003 Dec;1(3):E59. doi: 10.1371/journal.pbio.0000059. Epub 2003 Oct 27. PLoS Biol. 2003. PMID: 14691534 Free PMC article.
β4 Integrin signaling induces expansion of prostate tumor progenitors.
Yoshioka T, Otero J, Chen Y, Kim YM, Koutcher JA, Satagopan J, Reuter V, Carver B, de Stanchina E, Enomoto K, Greenberg NM, Scardino PT, Scher HI, Sawyers CL, Giancotti FG. Yoshioka T, et al. Among authors: koutcher ja. J Clin Invest. 2013 Feb;123(2):682-99. doi: 10.1172/JCI60720. Epub 2013 Jan 25. J Clin Invest. 2013. PMID: 23348745 Free PMC article.
Differential p53-independent outcomes of p19(Arf) loss in oncogenesis.
Chen Z, Carracedo A, Lin HK, Koutcher JA, Behrendt N, Egia A, Alimonti A, Carver BS, Gerald W, Teruya-Feldstein J, Loda M, Pandolfi PP. Chen Z, et al. Among authors: koutcher ja. Sci Signal. 2009 Aug 18;2(84):ra44. doi: 10.1126/scisignal.2000053. Sci Signal. 2009. PMID: 19690330 Free PMC article.
A critical role for choline kinase-alpha in the aggressiveness of bladder carcinomas.
Hernando E, Sarmentero-Estrada J, Koppie T, Belda-Iniesta C, Ramírez de Molina V, Cejas P, Ozu C, Le C, Sánchez JJ, González-Barón M, Koutcher J, Cordón-Cardó C, Bochner BH, Lacal JC, Ramírez de Molina A. Hernando E, et al. Oncogene. 2009 Jul 2;28(26):2425-35. doi: 10.1038/onc.2009.91. Epub 2009 May 18. Oncogene. 2009. PMID: 19448670 Free PMC article.
Single-dose radiotherapy disables tumor cell homologous recombination via ischemia/reperfusion injury.
Bodo S, Campagne C, Thin TH, Higginson DS, Vargas HA, Hua G, Fuller JD, Ackerstaff E, Russell J, Zhang Z, Klingler S, Cho H, Kaag MG, Mazaheri Y, Rimner A, Manova-Todorova K, Epel B, Zatcky J, Cleary CR, Rao SS, Yamada Y, Zelefsky MJ, Halpern HJ, Koutcher JA, Cordon-Cardo C, Greco C, Haimovitz-Friedman A, Sala E, Powell SN, Kolesnick R, Fuks Z. Bodo S, et al. Among authors: koutcher ja. J Clin Invest. 2019 Feb 1;129(2):786-801. doi: 10.1172/JCI97631. Epub 2019 Jan 14. J Clin Invest. 2019. PMID: 30480549 Free PMC article.
ETV4 promotes metastasis in response to activation of PI3-kinase and Ras signaling in a mouse model of advanced prostate cancer.
Aytes A, Mitrofanova A, Kinkade CW, Lefebvre C, Lei M, Phelan V, LeKaye HC, Koutcher JA, Cardiff RD, Califano A, Shen MM, Abate-Shen C. Aytes A, et al. Among authors: koutcher ja. Proc Natl Acad Sci U S A. 2013 Sep 10;110(37):E3506-15. doi: 10.1073/pnas.1303558110. Epub 2013 Aug 5. Proc Natl Acad Sci U S A. 2013. PMID: 23918374 Free PMC article.
227 results