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Insulin and glucocorticoid dependence of hepatic gamma-glutamylcysteine synthetase and glutathione synthesis in the rat. Studies in cultured hepatocytes and in vivo.
Lu SC, Ge JL, Kuhlenkamp J, Kaplowitz N. Lu SC, et al. Among authors: kaplowitz n. J Clin Invest. 1992 Aug;90(2):524-32. doi: 10.1172/JCI115890. J Clin Invest. 1992. PMID: 1353765 Free PMC article.
We reported that glucagon and phenylephrine decrease hepatocyte GSH by inhibiting gamma-glutamylcysteine synthetase (GCS), the rate-limiting enzyme in GSH synthesis (Lu, S.C., J. Kuhlenkamp, C. Garcia-Ruiz, and N. Kaplowitz. 1991. J. Clin. Invest. 88:260-269). In co …
We reported that glucagon and phenylephrine decrease hepatocyte GSH by inhibiting gamma-glutamylcysteine synthetase (GCS), the rate-limiting …
342 results