Venitt S - Search Results

1

Genotoxic potential of tamoxifen and analogues in female Fischer F344/n rats, DBA/2 and C57BL/6 mice and in human MCL-5 cells.

White IN, de Matteis F, Davies A, Smith LL, Crofton-Sleigh C, Venitt S, Hewer A, Phillips DH. White IN, et al. Among authors: venitt s. Carcinogenesis. 1992 Dec;13(12):2197-203. doi: 10.1093/carcin/13.12.2197. Carcinogenesis. 1992. PMID: 1473224

2

DNA damage in breast epithelial cells: detection by the single-cell gel (comet) assay and induction by human mammary lipid extracts.

Martin FL, Venitt S, Carmichael PL, Crofton-Sleigh C, Stone EM, Cole KJ, Gusterson BA, Grover PL, Phillips DH. Martin FL, et al. Among authors: venitt s. Carcinogenesis. 1997 Dec;18(12):2299-305. doi: 10.1093/carcin/18.12.2299. Carcinogenesis. 1997. PMID: 9450473

3

The metabolic activation of tamoxifen and alpha-hydroxytamoxifen to DNA-binding species in rat hepatocytes proceeds via sulphation.

Davis W, Venitt S, Phillips DH. Davis W, et al. Among authors: venitt s. Carcinogenesis. 1998 May;19(5):861-6. doi: 10.1093/carcin/19.5.861. Carcinogenesis. 1998. PMID: 9635875

4

Rat, but not human, sulfotransferase activates a tamoxifen metabolite to produce DNA adducts and gene mutations in bacteria and mammalian cells in culture.

Glatt H, Davis W, Meinl W, Hermersdörfer H, Venitt S, Phillips DH. Glatt H, et al. Among authors: venitt s. Carcinogenesis. 1998 Oct;19(10):1709-13. doi: 10.1093/carcin/19.10.1709. Carcinogenesis. 1998. PMID: 9806149

5

Reduced genotoxicity of [D5-ethyl]-tamoxifen implicates alpha-hydroxylation of the ethyl group as a major pathway of tamoxifen activation to a liver carcinogen.

Phillips DH, Potter GA, Horton MN, Hewer A, Crofton-Sleigh C, Jarman M, Venitt S. Phillips DH, et al. Among authors: venitt s. Carcinogenesis. 1994 Aug;15(8):1487-92. doi: 10.1093/carcin/15.8.1487. Carcinogenesis. 1994. PMID: 8055624

6

Genotoxicity of human mammary lipid.

Martin FL, Carmichael PL, Crofton-Sleigh C, Venitt S, Phillips DH, Grover PL. Martin FL, et al. Among authors: venitt s. Cancer Res. 1996 Dec 1;56(23):5342-6. Cancer Res. 1996. PMID: 8968081

7

Heterocyclic aromatic amines induce DNA strand breaks and cell transformation.

Pfau W, Martin FL, Cole KJ, Venitt S, Phillips DH, Grover PL, Marquardt H. Pfau W, et al. Among authors: venitt s. Carcinogenesis. 1999 Apr;20(4):545-51. doi: 10.1093/carcin/20.4.545. Carcinogenesis. 1999. PMID: 10223180

8

Micronucleus assays using cytochalasin-blocked MCL-5 cells, a proprietary human cell line expressing five human cytochromes P-450 and microsomal epoxide hydrolase.

Crofton-Sleigh C, Doherty A, Ellard S, Parry EM, Venitt S. Crofton-Sleigh C, et al. Among authors: venitt s. Mutagenesis. 1993 Jul;8(4):363-72. doi: 10.1093/mutage/8.4.363. Mutagenesis. 1993. PMID: 8377657

9

DNA and protein adducts in human tissues resulting from exposure to tobacco smoke.

Phillips DH, Venitt S. Phillips DH, et al. Among authors: venitt s. Int J Cancer. 2012 Dec 15;131(12):2733-53. doi: 10.1002/ijc.27827. Epub 2012 Oct 5. Int J Cancer. 2012. PMID: 22961407 Review.

10

Safety of prophylactic tamoxifen.

Phillips DH, Venitt S. Phillips DH, et al. Among authors: venitt s. Lancet. 1993 Jun 5;341(8858):1485-6. doi: 10.1016/0140-6736(93)90934-9. Lancet. 1993. PMID: 8099187 No abstract available.

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