Solomon LR - Search Results

1

Divergence of Genbank and human tumor Bcl-2 sequences and implications for binding affinity to key apoptotic proteins.

Joseph MK, Solomon LR, Petros AM, Cai J, Simmer RL, Zhang H, Rosenberg S, Ng SC. Joseph MK, et al. Among authors: solomon lr. Oncogene. 2004 Jan 22;23(3):835-8. doi: 10.1038/sj.onc.1207141. Oncogene. 2004. PMID: 14737118

2

Kringle 5 of human plasminogen induces apoptosis of endothelial and tumor cells through surface-expressed glucose-regulated protein 78.

Davidson DJ, Haskell C, Majest S, Kherzai A, Egan DA, Walter KA, Schneider A, Gubbins EF, Solomon L, Chen Z, Lesniewski R, Henkin J. Davidson DJ, et al. Cancer Res. 2005 Jun 1;65(11):4663-72. doi: 10.1158/0008-5472.CAN-04-3426. Cancer Res. 2005. PMID: 15930284

3

Structure of MurF from Streptococcus pneumoniae co-crystallized with a small molecule inhibitor exhibits interdomain closure.

Longenecker KL, Stamper GF, Hajduk PJ, Fry EH, Jakob CG, Harlan JE, Edalji R, Bartley DM, Walter KA, Solomon LR, Holzman TF, Gu YG, Lerner CG, Beutel BA, Stoll VS. Longenecker KL, et al. Among authors: solomon lr. Protein Sci. 2005 Dec;14(12):3039-47. doi: 10.1110/ps.051604805. Protein Sci. 2005. PMID: 16322581 Free PMC article.

4

Structural characterization of a soluble amyloid beta-peptide oligomer.

Yu L, Edalji R, Harlan JE, Holzman TF, Lopez AP, Labkovsky B, Hillen H, Barghorn S, Ebert U, Richardson PL, Miesbauer L, Solomon L, Bartley D, Walter K, Johnson RW, Hajduk PJ, Olejniczak ET. Yu L, et al. Biochemistry. 2009 Mar 10;48(9):1870-7. doi: 10.1021/bi802046n. Biochemistry. 2009. PMID: 19216516

5

Design of adenosine kinase inhibitors from the NMR-based screening of fragments.

Hajduk PJ, Gomtsyan A, Didomenico S, Cowart M, Bayburt EK, Solomon L, Severin J, Smith R, Walter K, Holzman TF, Stewart A, McGaraughty S, Jarvis MF, Kowaluk EA, Fesik SW. Hajduk PJ, et al. J Med Chem. 2000 Dec 14;43(25):4781-6. doi: 10.1021/jm000373a. J Med Chem. 2000. PMID: 11123986

6

Solution structure and mutational analysis of pituitary adenylate cyclase-activating polypeptide binding to the extracellular domain of PAC1-RS.

Sun C, Song D, Davis-Taber RA, Barrett LW, Scott VE, Richardson PL, Pereda-Lopez A, Uchic ME, Solomon LR, Lake MR, Walter KA, Hajduk PJ, Olejniczak ET. Sun C, et al. Among authors: solomon lr. Proc Natl Acad Sci U S A. 2007 May 8;104(19):7875-80. doi: 10.1073/pnas.0611397104. Epub 2007 Apr 30. Proc Natl Acad Sci U S A. 2007. PMID: 17470806 Free PMC article.

7

Iniparib nonselectively modifies cysteine-containing proteins in tumor cells and is not a bona fide PARP inhibitor.

Liu X, Shi Y, Maag DX, Palma JP, Patterson MJ, Ellis PA, Surber BW, Ready DB, Soni NB, Ladror US, Xu AJ, Iyer R, Harlan JE, Solomon LR, Donawho CK, Penning TD, Johnson EF, Shoemaker AR. Liu X, et al. Among authors: solomon lr. Clin Cancer Res. 2012 Jan 15;18(2):510-23. doi: 10.1158/1078-0432.CCR-11-1973. Epub 2011 Nov 29. Clin Cancer Res. 2012. PMID: 22128301

8

Hexavalent TRAIL Fusion Protein Eftozanermin Alfa Optimally Clusters Apoptosis-Inducing TRAIL Receptors to Induce On-Target Antitumor Activity in Solid Tumors.

Phillips DC, Buchanan FG, Cheng D, Solomon LR, Xiao Y, Xue J, Tahir SK, Smith ML, Zhang H, Widomski D, Abraham VC, Xu N, Liu Z, Zhou L, DiGiammarino E, Lu X, Rudra-Ganguly N, Trela B, Morgan-Lappe SE. Phillips DC, et al. Among authors: solomon lr. Cancer Res. 2021 Jun 15;81(12):3402-3414. doi: 10.1158/0008-5472.CAN-20-2178. Epub 2021 Mar 9. Cancer Res. 2021. PMID: 33687950

9

Investigating the origin of the slow-binding inhibition of HCV NS3 serine protease by a novel substrate based inhibitor.

Liu Y, Saldivar A, Bess J, Solomon L, Chen CM, Tripathi R, Barrett L, Richardson PL, Molla A, Kohlbrenner W, Kati W. Liu Y, et al. Biochemistry. 2003 Jul 29;42(29):8862-9. doi: 10.1021/bi034661v. Biochemistry. 2003. PMID: 12873147

10

Initial characterization of autoprocessing and active-center mutants of CMV proteinase.

Snyder SW, Edalji RP, Lindh FG, Walter KA, Solomon L, Pratt S, Steffy K, Holzman TF. Snyder SW, et al. J Protein Chem. 1996 Nov;15(8):763-74. doi: 10.1007/BF01887151. J Protein Chem. 1996. PMID: 9008301

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