Griffey R - Search Results

1

Synthesis and evaluation of novel bacterial rRNA-binding benzimidazoles by mass spectrometry.

He Y, Yang J, Wu B, Robinson D, Sprankle K, Kung PP, Lowery K, Mohan V, Hofstadler S, Swayze EE, Griffey R. He Y, et al. Among authors: griffey r. Bioorg Med Chem Lett. 2004 Feb 9;14(3):695-9. doi: 10.1016/j.bmcl.2003.11.031. Bioorg Med Chem Lett. 2004. PMID: 14741271

2

Synthesis of linked carbohydrates and evaluation of their binding for 16S RNA by mass spectrometry.

Wu B, Yang J, Robinson D, Hofstadler S, Griffey R, Swayze EE, He Y. Wu B, et al. Among authors: griffey r. Bioorg Med Chem Lett. 2003 Nov 17;13(22):3915-8. doi: 10.1016/j.bmcl.2003.09.005. Bioorg Med Chem Lett. 2003. PMID: 14592474

3

SAR by MS: a ligand based technique for drug lead discovery against structured RNA targets.

Swayze EE, Jefferson EA, Sannes-Lowery KA, Blyn LB, Risen LM, Arakawa S, Osgood SA, Hofstadler SA, Griffey RH. Swayze EE, et al. J Med Chem. 2002 Aug 29;45(18):3816-9. doi: 10.1021/jm0255466. J Med Chem. 2002. PMID: 12190303

4

SAR by MS: discovery of a new class of RNA-binding small molecules for the hepatitis C virus: internal ribosome entry site IIA subdomain.

Seth PP, Miyaji A, Jefferson EA, Sannes-Lowery KA, Osgood SA, Propp SS, Ranken R, Massire C, Sampath R, Ecker DJ, Swayze EE, Griffey RH. Seth PP, et al. Among authors: griffey rh. J Med Chem. 2005 Nov 17;48(23):7099-102. doi: 10.1021/jm050815o. J Med Chem. 2005. PMID: 16279767

5

Determinants of aminoglycoside-binding specificity for rRNA by using mass spectrometry.

Griffey RH, Hofstadler SA, Sannes-Lowery KA, Ecker DJ, Crooke ST. Griffey RH, et al. Proc Natl Acad Sci U S A. 1999 Aug 31;96(18):10129-33. doi: 10.1073/pnas.96.18.10129. Proc Natl Acad Sci U S A. 1999. PMID: 10468574 Free PMC article.

6

Fully 2'-modified oligonucleotide duplexes with improved in vitro potency and stability compared to unmodified small interfering RNA.

Allerson CR, Sioufi N, Jarres R, Prakash TP, Naik N, Berdeja A, Wanders L, Griffey RH, Swayze EE, Bhat B. Allerson CR, et al. Among authors: griffey rh. J Med Chem. 2005 Feb 24;48(4):901-4. doi: 10.1021/jm049167j. J Med Chem. 2005. PMID: 15715458

7

An efficient synthesis of gougerotin and related analogues using solid- and solution-phase methodology.

Migawa MT, Risen LM, Griffey RH, Swayze EE. Migawa MT, et al. Org Lett. 2005 Aug 4;7(16):3429-32. doi: 10.1021/ol0507322. Org Lett. 2005. PMID: 16048309

8

Structure-activity relationship study on a simple cationic peptide motif for cellular delivery of antisense peptide nucleic acid.

Albertshofer K, Siwkowski AM, Wancewicz EV, Esau CC, Watanabe T, Nishihara KC, Kinberger GA, Malik L, Eldrup AB, Manoharan M, Geary RS, Monia BP, Swayze EE, Griffey RH, Bennett CF, Maier MA. Albertshofer K, et al. J Med Chem. 2005 Oct 20;48(21):6741-9. doi: 10.1021/jm050490b. J Med Chem. 2005. PMID: 16220989

9

Improving RNA interference in mammalian cells by 4'-thio-modified small interfering RNA (siRNA): effect on siRNA activity and nuclease stability when used in combination with 2'-O-alkyl modifications.

Dande P, Prakash TP, Sioufi N, Gaus H, Jarres R, Berdeja A, Swayze EE, Griffey RH, Bhat B. Dande P, et al. Among authors: griffey rh. J Med Chem. 2006 Mar 9;49(5):1624-34. doi: 10.1021/jm050822c. J Med Chem. 2006. PMID: 16509579

10

Evaluation of basic amphipathic peptides for cellular delivery of antisense peptide nucleic acids.

Maier MA, Esau CC, Siwkowski AM, Wancewicz EV, Albertshofer K, Kinberger GA, Kadaba NS, Watanabe T, Manoharan M, Bennett CF, Griffey RH, Swayze EE. Maier MA, et al. J Med Chem. 2006 Apr 20;49(8):2534-42. doi: 10.1021/jm051275y. J Med Chem. 2006. PMID: 16610796

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