Hofstadler S - Search Results

1

Synthesis and evaluation of novel bacterial rRNA-binding benzimidazoles by mass spectrometry.

He Y, Yang J, Wu B, Robinson D, Sprankle K, Kung PP, Lowery K, Mohan V, Hofstadler S, Swayze EE, Griffey R. He Y, et al. Among authors: hofstadler s. Bioorg Med Chem Lett. 2004 Feb 9;14(3):695-9. doi: 10.1016/j.bmcl.2003.11.031. Bioorg Med Chem Lett. 2004. PMID: 14741271

2

Synthesis of linked carbohydrates and evaluation of their binding for 16S RNA by mass spectrometry.

Wu B, Yang J, Robinson D, Hofstadler S, Griffey R, Swayze EE, He Y. Wu B, et al. Among authors: hofstadler s. Bioorg Med Chem Lett. 2003 Nov 17;13(22):3915-8. doi: 10.1016/j.bmcl.2003.09.005. Bioorg Med Chem Lett. 2003. PMID: 14592474

3

SAR by MS: a ligand based technique for drug lead discovery against structured RNA targets.

Swayze EE, Jefferson EA, Sannes-Lowery KA, Blyn LB, Risen LM, Arakawa S, Osgood SA, Hofstadler SA, Griffey RH. Swayze EE, et al. Among authors: hofstadler sa. J Med Chem. 2002 Aug 29;45(18):3816-9. doi: 10.1021/jm0255466. J Med Chem. 2002. PMID: 12190303

4

Determinants of aminoglycoside-binding specificity for rRNA by using mass spectrometry.

Griffey RH, Hofstadler SA, Sannes-Lowery KA, Ecker DJ, Crooke ST. Griffey RH, et al. Among authors: hofstadler sa. Proc Natl Acad Sci U S A. 1999 Aug 31;96(18):10129-33. doi: 10.1073/pnas.96.18.10129. Proc Natl Acad Sci U S A. 1999. PMID: 10468574 Free PMC article.

5

Multiplexed screening of neutral mass-tagged RNA targets against ligand libraries with electrospray ionization FTICR MS: a paradigm for high-throughput affinity screening.

Hofstadler SA, Sannes-Lowery KA, Crooke ST, Ecker DJ, Sasmor H, Manalili S, Griffey RH. Hofstadler SA, et al. Anal Chem. 1999 Aug 15;71(16):3436-40. doi: 10.1021/ac990262n. Anal Chem. 1999. PMID: 10464476

6

Measuring dissociation constants of RNA and aminoglycoside antibiotics by electrospray ionization mass spectrometry.

Sannes-Lowery KA, Griffey RH, Hofstadler SA. Sannes-Lowery KA, et al. Among authors: hofstadler sa. Anal Biochem. 2000 May 1;280(2):264-71. doi: 10.1006/abio.2000.4550. Anal Biochem. 2000. PMID: 10790309

7

An efficient synthesis of mimetics of neamine for RNA recognition.

Ding Y, Hofstadler SA, Swayze EE, Griffey RH. Ding Y, et al. Among authors: hofstadler sa. Org Lett. 2001 May 31;3(11):1621-3. doi: 10.1021/ol015794g. Org Lett. 2001. PMID: 11405670

8

Analysis of noncovalent complexes of DNA and RNA by mass spectrometry.

Hofstadler SA, Griffey RH. Hofstadler SA, et al. Chem Rev. 2001 Feb;101(2):377-90. doi: 10.1021/cr990105o. Chem Rev. 2001. PMID: 11712252 Review. No abstract available.

9

Mass spectrometry as a drug discovery platform against RNA targets.

Hofstadler SA, Griffey RH. Hofstadler SA, et al. Curr Opin Drug Discov Devel. 2000 Jul;3(4):423-31. Curr Opin Drug Discov Devel. 2000. PMID: 19649873

10

Design and synthesis of paromomycin-related heterocycle-substituted aminoglycoside mimetics based on a mass spectrometry RNA-binding assay.

Ding Y, Hofstadler SA, Swayze EE, Risen L, Griffey RH. Ding Y, et al. Angew Chem Int Ed Engl. 2003 Jul 28;42(29):3409-12. doi: 10.1002/anie.200351354. Angew Chem Int Ed Engl. 2003. PMID: 12888972 No abstract available.

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