Tortorella D - Search Results

1

Dissection of the dislocation pathway for type I membrane proteins with a new small molecule inhibitor, eeyarestatin.

Fiebiger E, Hirsch C, Vyas JM, Gordon E, Ploegh HL, Tortorella D. Fiebiger E, et al. Among authors: tortorella d. Mol Biol Cell. 2004 Apr;15(4):1635-46. doi: 10.1091/mbc.e03-07-0506. Epub 2004 Feb 6. Mol Biol Cell. 2004. PMID: 14767067 Free PMC article.

2

Visualization of the ER-to-cytosol dislocation reaction of a type I membrane protein.

Fiebiger E, Story C, Ploegh HL, Tortorella D. Fiebiger E, et al. Among authors: tortorella d. EMBO J. 2002 Mar 1;21(5):1041-53. doi: 10.1093/emboj/21.5.1041. EMBO J. 2002. PMID: 11867532 Free PMC article.

3

Protein unfolding is not a prerequisite for endoplasmic reticulum-to-cytosol dislocation.

Tirosh B, Furman MH, Tortorella D, Ploegh HL. Tirosh B, et al. Among authors: tortorella d. J Biol Chem. 2003 Feb 28;278(9):6664-72. doi: 10.1074/jbc.M210158200. Epub 2002 Dec 12. J Biol Chem. 2003. PMID: 12482753 Free article.

4

Ubiquitinylation of the cytosolic domain of a type I membrane protein is not required to initiate its dislocation from the endoplasmic reticulum.

Furman MH, Loureiro J, Ploegh HL, Tortorella D. Furman MH, et al. Among authors: tortorella d. J Biol Chem. 2003 Sep 12;278(37):34804-11. doi: 10.1074/jbc.M300913200. Epub 2003 Jun 27. J Biol Chem. 2003. PMID: 12832421 Free article.

5

Dislocation of a type I membrane protein requires interactions between membrane-spanning segments within the lipid bilayer.

Lilley BN, Tortorella D, Ploegh HL. Lilley BN, et al. Among authors: tortorella d. Mol Biol Cell. 2003 Sep;14(9):3690-8. doi: 10.1091/mbc.e03-03-0192. Epub 2003 Jun 13. Mol Biol Cell. 2003. PMID: 12972557 Free PMC article.

6

A glycosylated type I membrane protein becomes cytosolic when peptide: N-glycanase is compromised.

Blom D, Hirsch C, Stern P, Tortorella D, Ploegh HL. Blom D, et al. Among authors: tortorella d. EMBO J. 2004 Feb 11;23(3):650-8. doi: 10.1038/sj.emboj.7600090. Epub 2004 Jan 29. EMBO J. 2004. PMID: 14749736 Free PMC article.

7

Signal peptide peptidase is required for dislocation from the endoplasmic reticulum.

Loureiro J, Lilley BN, Spooner E, Noriega V, Tortorella D, Ploegh HL. Loureiro J, et al. Among authors: tortorella d. Nature. 2006 Jun 15;441(7095):894-7. doi: 10.1038/nature04830. Epub 2006 May 31. Nature. 2006. PMID: 16738546

8

Dislocation of type I membrane proteins from the ER to the cytosol is sensitive to changes in redox potential.

Tortorella D, Story CM, Huppa JB, Wiertz EJ, Jones TR, Bacik I, Bennink JR, Yewdell JW, Ploegh HL. Tortorella D, et al. J Cell Biol. 1998 Jul 27;142(2):365-76. doi: 10.1083/jcb.142.2.365. J Cell Biol. 1998. PMID: 9679137 Free PMC article.

9

Extended peptide-based inhibitors efficiently target the proteasome and reveal overlapping specificities of the catalytic beta-subunits.

Kessler BM, Tortorella D, Altun M, Kisselev AF, Fiebiger E, Hekking BG, Ploegh HL, Overkleeft HS. Kessler BM, et al. Among authors: tortorella d. Chem Biol. 2001 Sep;8(9):913-29. doi: 10.1016/s1074-5521(01)00069-2. Chem Biol. 2001. PMID: 11564559

10

Membrane-specific, host-derived factors are required for US2- and US11-mediated degradation of major histocompatibility complex class I molecules.

Furman MH, Ploegh HL, Tortorella D. Furman MH, et al. Among authors: tortorella d. J Biol Chem. 2002 Feb 1;277(5):3258-67. doi: 10.1074/jbc.M109765200. Epub 2001 Nov 20. J Biol Chem. 2002. PMID: 11717308 Free article.

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