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The Polo-Like Kinase 1 (PLK1) inhibitor NMS-P937 is effective in a new model of disseminated primary CD56+ acute monoblastic leukaemia.
Casolaro A, Golay J, Albanese C, Ceruti R, Patton V, Cribioli S, Pezzoni A, Losa M, Texido G, Giussani U, Marchesi F, Amboldi N, Valsasina B, Bungaro S, Cazzaniga G, Rambaldi A, Introna M, Pesenti E, Alzani R. Casolaro A, et al. Among authors: pezzoni a. PLoS One. 2013;8(3):e58424. doi: 10.1371/journal.pone.0058424. Epub 2013 Mar 8. PLoS One. 2013. PMID: 23520509 Free PMC article. Clinical Trial.
Phosphorylation of TCTP as a marker for polo-like kinase-1 activity in vivo.
Cucchi U, Gianellini LM, De Ponti A, Sola F, Alzani R, Patton V, Pezzoni A, Troiani S, Saccardo MB, Rizzi S, Giorgini ML, Cappella P, Beria I, Valsasina B. Cucchi U, et al. Among authors: pezzoni a. Anticancer Res. 2010 Dec;30(12):4973-85. Anticancer Res. 2010. PMID: 21187478