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PKC-alpha regulates cardiac contractility and propensity toward heart failure.
Braz JC, Gregory K, Pathak A, Zhao W, Sahin B, Klevitsky R, Kimball TF, Lorenz JN, Nairn AC, Liggett SB, Bodi I, Wang S, Schwartz A, Lakatta EG, DePaoli-Roach AA, Robbins J, Hewett TE, Bibb JA, Westfall MV, Kranias EG, Molkentin JD. Braz JC, et al. Among authors: klevitsky r. Nat Med. 2004 Mar;10(3):248-54. doi: 10.1038/nm1000. Epub 2004 Feb 15. Nat Med. 2004. PMID: 14966518 Free article.
Pharmacological- and gene therapy-based inhibition of protein kinase Calpha/beta enhances cardiac contractility and attenuates heart failure.
Hambleton M, Hahn H, Pleger ST, Kuhn MC, Klevitsky R, Carr AN, Kimball TF, Hewett TE, Dorn GW 2nd, Koch WJ, Molkentin JD. Hambleton M, et al. Among authors: klevitsky r. Circulation. 2006 Aug 8;114(6):574-82. doi: 10.1161/CIRCULATIONAHA.105.592550. Epub 2006 Jul 31. Circulation. 2006. PMID: 16880328 Free PMC article.
Analysis of myosin heavy chain functionality in the heart.
Krenz M, Sanbe A, Bouyer-Dalloz F, Gulick J, Klevitsky R, Hewett TE, Osinska HE, Lorenz JN, Brosseau C, Federico A, Alpert NR, Warshaw DM, Perryman MB, Helmke SM, Robbins J. Krenz M, et al. Among authors: klevitsky r. J Biol Chem. 2003 May 9;278(19):17466-74. doi: 10.1074/jbc.M210804200. Epub 2003 Mar 6. J Biol Chem. 2003. PMID: 12626511 Free article.
47 results