Micklefield J - Search Results

1

Nucleic acid binding properties of thyminyl and adeninyl pyrrolidine-amide oligonucleotide mimics (POM).

Tan TH, Hickman DT, Morral J, Beadham IG, Micklefield J. Tan TH, et al. Among authors: micklefield j. Chem Commun (Camb). 2004 Mar 7;(5):516-7. doi: 10.1039/b315768g. Epub 2004 Jan 28. Chem Commun (Camb). 2004. PMID: 14973585

2

Searching for the optimal microbial factory: high-throughput biosensors and analytical techniques for screening small molecules.

O'Connor E, Micklefield J, Cai Y. O'Connor E, et al. Among authors: micklefield j. Curr Opin Biotechnol. 2024 Jun;87:103125. doi: 10.1016/j.copbio.2024.103125. Epub 2024 Mar 27. Curr Opin Biotechnol. 2024. PMID: 38547587 Free article. Review.

3

Kinetically selective binding of single stranded RNA over DNA by a pyrrolidine-amide oligonucleotide mimic (POM).

Hickman DT, King PM, Slater JM, Cooper MA, Micklefield J. Hickman DT, et al. Among authors: micklefield j. Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20(4-7):1169-72. doi: 10.1081/NCN-100002512. Nucleosides Nucleotides Nucleic Acids. 2001. PMID: 11562979

4

Design, synthesis, conformational analysis and nucleic acid hybridisation properties of thymidyl pyrrolidine-amide oligonucleotide mimics (POM).

Hickman DT, Tan TH, Morral J, King PM, Cooper MA, Micklefield J. Hickman DT, et al. Among authors: micklefield j. Org Biomol Chem. 2003 Oct 7;1(19):3277-92. doi: 10.1039/b306156f. Org Biomol Chem. 2003. PMID: 14584791

5

Stereospecific backbone methylation of pyrrolidine-amide oligonucleotide mimics (POM).

Khan AI, Tan TH, Micklefield J. Khan AI, et al. Among authors: micklefield j. Chem Commun (Camb). 2006 Apr 7;(13):1436-8. doi: 10.1039/b518171b. Epub 2006 Feb 23. Chem Commun (Camb). 2006. PMID: 16550292

6

Homopolymeric pyrrolidine-amide oligonucleotide mimics: Fmoc-synthesis and DNA/RNA binding properties.

Tan TH, Worthington RJ, Pritchard RG, Morral J, Micklefield J. Tan TH, et al. Among authors: micklefield j. Org Biomol Chem. 2007 Jan 21;5(2):239-48. doi: 10.1039/b613384n. Epub 2006 Dec 1. Org Biomol Chem. 2007. PMID: 17205167

7

Mixed-sequence pyrrolidine-amide oligonucleotide mimics: Boc(Z) synthesis and DNA/RNA binding properties.

Worthington RJ, O'Rourke AP, Morral J, Tan TH, Micklefield J. Worthington RJ, et al. Among authors: micklefield j. Org Biomol Chem. 2007 Jan 21;5(2):249-59. doi: 10.1039/b613386j. Epub 2006 Dec 1. Org Biomol Chem. 2007. PMID: 17205168

8

Precursor-directed biosynthesis of nonribosomal lipopeptides with modified glutamate residues.

Powell A, Al Nakeeb M, Wilkinson B, Micklefield J. Powell A, et al. Among authors: micklefield j. Chem Commun (Camb). 2007 Jul 14;(26):2683-5. doi: 10.1039/b706224a. Epub 2007 May 29. Chem Commun (Camb). 2007. PMID: 17594019

9

RNA-selective cross-pairing of backbone-extended pyrrolidine-amide oligonucleotide mimics (bePOMs).

Worthington RJ, Bell NM, Wong R, Micklefield J. Worthington RJ, et al. Among authors: micklefield j. Org Biomol Chem. 2008 Jan 7;6(1):92-103. doi: 10.1039/b714580m. Epub 2007 Nov 1. Org Biomol Chem. 2008. PMID: 18075653

10

Biophysical and cellular-uptake properties of mixed-sequence pyrrolidine-amide oligonucleotide mimics.

Worthington RJ, Micklefield J. Worthington RJ, et al. Among authors: micklefield j. Chemistry. 2011 Dec 16;17(51):14429-41. doi: 10.1002/chem.201101950. Epub 2011 Nov 11. Chemistry. 2011. PMID: 22076794

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