Simon RH - Search Results

1

The plasminogen activation system reduces fibrosis in the lung by a hepatocyte growth factor-dependent mechanism.

Hattori N, Mizuno S, Yoshida Y, Chin K, Mishima M, Sisson TH, Simon RH, Nakamura T, Miyake M. Hattori N, et al. Among authors: simon rh. Am J Pathol. 2004 Mar;164(3):1091-8. doi: 10.1016/S0002-9440(10)63196-3. Am J Pathol. 2004. PMID: 14982862 Free PMC article.

2

Inducible lung-specific urokinase expression reduces fibrosis and mortality after lung injury in mice.

Sisson TH, Hanson KE, Subbotina N, Patwardhan A, Hattori N, Simon RH. Sisson TH, et al. Among authors: simon rh. Am J Physiol Lung Cell Mol Physiol. 2002 Nov;283(5):L1023-32. doi: 10.1152/ajplung.00049.2002. Am J Physiol Lung Cell Mol Physiol. 2002. PMID: 12376355 Free article.

3

Reduction in fibrotic tissue formation in mice genetically deficient in plasminogen activator inhibitor-1.

Chuang-Tsai S, Sisson TH, Hattori N, Tsai CG, Subbotina NM, Hanson KE, Simon RH. Chuang-Tsai S, et al. Among authors: simon rh. Am J Pathol. 2003 Aug;163(2):445-52. doi: 10.1016/S0002-9440(10)63674-7. Am J Pathol. 2003. PMID: 12875966 Free PMC article.

4

Localization of plasminogen activator activity within normal and injured lungs by in situ zymography.

Nishiuma T, Sisson TH, Subbotina N, Simon RH. Nishiuma T, et al. Among authors: simon rh. Am J Respir Cell Mol Biol. 2004 Nov;31(5):552-8. doi: 10.1165/rcmb.2004-0162OC. Epub 2004 Jul 29. Am J Respir Cell Mol Biol. 2004. PMID: 15284078

5

Plasminogen-mediated activation and release of hepatocyte growth factor from extracellular matrix.

Matsuoka H, Sisson TH, Nishiuma T, Simon RH. Matsuoka H, et al. Among authors: simon rh. Am J Respir Cell Mol Biol. 2006 Dec;35(6):705-13. doi: 10.1165/rcmb.2006-0006OC. Epub 2006 Jul 13. Am J Respir Cell Mol Biol. 2006. PMID: 16840775 Free PMC article.

6

Plasminogen activation induced pericellular fibronectin proteolysis promotes fibroblast apoptosis.

Horowitz JC, Rogers DS, Simon RH, Sisson TH, Thannickal VJ. Horowitz JC, et al. Among authors: simon rh. Am J Respir Cell Mol Biol. 2008 Jan;38(1):78-87. doi: 10.1165/rcmb.2007-0174OC. Epub 2007 Jul 26. Am J Respir Cell Mol Biol. 2008. PMID: 17656680 Free PMC article.

7

Inhalation of urokinase-type plasminogen activator reduces airway remodeling in a murine asthma model.

Kuramoto E, Nishiuma T, Kobayashi K, Yamamoto M, Kono Y, Funada Y, Kotani Y, Sisson TH, Simon RH, Nishimura Y. Kuramoto E, et al. Among authors: simon rh. Am J Physiol Lung Cell Mol Physiol. 2009 Mar;296(3):L337-46. doi: 10.1152/ajplung.90434.2008. Epub 2008 Dec 19. Am J Physiol Lung Cell Mol Physiol. 2009. PMID: 19098125 Free article.

8

Urokinase-type plasminogen activator increases hepatocyte growth factor activity required for skeletal muscle regeneration.

Sisson TH, Nguyen MH, Yu B, Novak ML, Simon RH, Koh TJ. Sisson TH, et al. Among authors: simon rh. Blood. 2009 Dec 3;114(24):5052-61. doi: 10.1182/blood-2008-12-196212. Epub 2009 Oct 7. Blood. 2009. PMID: 19812386 Free PMC article.

9

PAI-1 promotes the accumulation of exudate macrophages and worsens pulmonary fibrosis following type II alveolar epithelial cell injury.

Osterholzer JJ, Christensen PJ, Lama V, Horowitz JC, Hattori N, Subbotina N, Cunningham A, Lin Y, Murdock BJ, Morey RE, Olszewski MA, Lawrence DA, Simon RH, Sisson TH. Osterholzer JJ, et al. Among authors: simon rh. J Pathol. 2012 Oct;228(2):170-80. doi: 10.1002/path.3992. Epub 2012 Jun 6. J Pathol. 2012. PMID: 22262246 Free PMC article.

10

Treatment of bleomycin-induced pulmonary fibrosis by transfer of urokinase-type plasminogen activator genes.

Sisson TH, Hattori N, Xu Y, Simon RH. Sisson TH, et al. Among authors: simon rh. Hum Gene Ther. 1999 Sep 20;10(14):2315-23. doi: 10.1089/10430349950016960. Hum Gene Ther. 1999. PMID: 10515451

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