Peschard P - Search Results

1

The Shc adaptor protein is critical for VEGF induction by Met/HGF and ErbB2 receptors and for early onset of tumor angiogenesis.

Saucier C, Khoury H, Lai KM, Peschard P, Dankort D, Naujokas MA, Holash J, Yancopoulos GD, Muller WJ, Pawson T, Park M. Saucier C, et al. Among authors: peschard p. Proc Natl Acad Sci U S A. 2004 Feb 24;101(8):2345-50. doi: 10.1073/pnas.0308065101. Proc Natl Acad Sci U S A. 2004. PMID: 14983012 Free PMC article.

2

Met/Hepatocyte growth factor receptor ubiquitination suppresses transformation and is required for Hrs phosphorylation.

Abella JV, Peschard P, Naujokas MA, Lin T, Saucier C, Urbé S, Park M. Abella JV, et al. Among authors: peschard p. Mol Cell Biol. 2005 Nov;25(21):9632-45. doi: 10.1128/MCB.25.21.9632-9645.2005. Mol Cell Biol. 2005. PMID: 16227611 Free PMC article.

3

From Tpr-Met to Met, tumorigenesis and tubes.

Peschard P, Park M. Peschard P, et al. Oncogene. 2007 Feb 26;26(9):1276-85. doi: 10.1038/sj.onc.1210201. Oncogene. 2007. PMID: 17322912 Review.

4

Escape from Cbl-mediated downregulation: a recurrent theme for oncogenic deregulation of receptor tyrosine kinases.

Peschard P, Park M. Peschard P, et al. Cancer Cell. 2003 Jun;3(6):519-23. doi: 10.1016/s1535-6108(03)00136-3. Cancer Cell. 2003. PMID: 12842080 Free article.

5

A conserved DpYR motif in the juxtamembrane domain of the Met receptor family forms an atypical c-Cbl/Cbl-b tyrosine kinase binding domain binding site required for suppression of oncogenic activation.

Peschard P, Ishiyama N, Lin T, Lipkowitz S, Park M. Peschard P, et al. J Biol Chem. 2004 Jul 9;279(28):29565-71. doi: 10.1074/jbc.M403954200. Epub 2004 Apr 29. J Biol Chem. 2004. PMID: 15123609 Free article.

6

Mutation of the c-Cbl TKB domain binding site on the Met receptor tyrosine kinase converts it into a transforming protein.

Peschard P, Fournier TM, Lamorte L, Naujokas MA, Band H, Langdon WY, Park M. Peschard P, et al. Mol Cell. 2001 Nov;8(5):995-1004. doi: 10.1016/s1097-2765(01)00378-1. Mol Cell. 2001. PMID: 11741535 Free article.

7

Oncogenic activation of the Met receptor tyrosine kinase fusion protein, Tpr-Met, involves exclusion from the endocytic degradative pathway.

Mak HH, Peschard P, Lin T, Naujokas MA, Zuo D, Park M. Mak HH, et al. Among authors: peschard p. Oncogene. 2007 Nov 8;26(51):7213-21. doi: 10.1038/sj.onc.1210522. Epub 2007 May 28. Oncogene. 2007. PMID: 17533376

8

LC3C-Mediated Autophagy Selectively Regulates the Met RTK and HGF-Stimulated Migration and Invasion.

Bell ES, Coelho PP, Ratcliffe CDH, Rajadurai CV, Peschard P, Vaillancourt R, Zuo D, Park M. Bell ES, et al. Among authors: peschard p. Cell Rep. 2019 Dec 17;29(12):4053-4068.e6. doi: 10.1016/j.celrep.2019.11.063. Cell Rep. 2019. PMID: 31851933 Free article.

9

Structural basis for UBA-mediated dimerization of c-Cbl ubiquitin ligase.

Kozlov G, Peschard P, Zimmerman B, Lin T, Moldoveanu T, Mansur-Azzam N, Gehring K, Park M. Kozlov G, et al. Among authors: peschard p. J Biol Chem. 2007 Sep 14;282(37):27547-27555. doi: 10.1074/jbc.M703333200. Epub 2007 Jul 16. J Biol Chem. 2007. PMID: 17635922 Free article.

10

Structural basis for ubiquitin-mediated dimerization and activation of the ubiquitin protein ligase Cbl-b.

Peschard P, Kozlov G, Lin T, Mirza IA, Berghuis AM, Lipkowitz S, Park M, Gehring K. Peschard P, et al. Mol Cell. 2007 Aug 3;27(3):474-85. doi: 10.1016/j.molcel.2007.06.023. Mol Cell. 2007. PMID: 17679095 Free article.

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