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The impact of estradiol on bone mineral density is modulated by the specific estrogen receptor-alpha cofactor retinoblastoma-interacting zinc finger protein-1 insertion/deletion polymorphism.
Grundberg E, Akesson K, Kindmark A, Gerdhem P, Holmberg A, Mellström D, Ljunggren O, Orwoll E, Mallmin H, Ohlsson C, Brändström H. Grundberg E, et al. Among authors: brandstrom h. J Clin Endocrinol Metab. 2007 Jun;92(6):2300-6. doi: 10.1210/jc.2006-1572. Epub 2007 Mar 13. J Clin Endocrinol Metab. 2007. PMID: 17356055
A single nucleotide polymorphism in the promoter region of the osteoprotegerin gene is related to intima-media thickness of the carotid artery in hypertensive patients. The Swedish Irbesartan Left Ventricular Hypertrophy Investigation vs Atenolol (SILVHIA).
Brändström H, Stiger F, Kahan T, Melhus H, Nyström F, öHman KP, Malmqvist K, Lind L, Kindmark A. Brändström H, et al. Blood Press. 2004;13(3):152-7. doi: 10.1080/08037050410035563. Blood Press. 2004. PMID: 15223723 Free article. Clinical Trial.
Polymorphisms in the CYP19 and AR genes--relation to bone mass and longitudinal bone changes in postmenopausal women with or without hormone replacement therapy: The Danish Osteoporosis Prevention Study.
Tofteng CL, Kindmark A, Brändström H, Abrahamsen B, Petersen S, Stiger F, Stilgren LS, Jensen JE, Vestergaard P, Langdahl BL, Mosekilde L; Danish Osteoporosis Prevention Study. Tofteng CL, et al. Among authors: brandstrom h. Calcif Tissue Int. 2004 Jan;74(1):25-34. doi: 10.1007/s00223-002-2158-3. Epub 2003 Oct 2. Calcif Tissue Int. 2004. PMID: 14517714 Clinical Trial.
A deletion polymorphism in the RIZ gene, a female sex steroid hormone receptor coactivator, exhibits decreased response to estrogen in vitro and associates with low bone mineral density in young Swedish women.
Grundberg E, Carling T, Brändström H, Huang S, Ribom EL, Ljunggren O, Mallmin H, Kindmark A. Grundberg E, et al. Among authors: brandstrom h. J Clin Endocrinol Metab. 2004 Dec;89(12):6173-8. doi: 10.1210/jc.2004-0403. J Clin Endocrinol Metab. 2004. PMID: 15579774
60 results