Orr DC - Search Results

1

Penicillin derived C2-symmetric dimers as novel inhibitors of HIV-1 proteinase.

Humber DC, Cammack N, Coates JA, Cobley KN, Orr DC, Storer R, Weingarten GG, Weir MP. Humber DC, et al. Among authors: orr dc. J Med Chem. 1992 Aug 7;35(16):3080-1. doi: 10.1021/jm00094a024. J Med Chem. 1992. PMID: 1501235 No abstract available.

2

Synthesis and anti-HIV-1 activity of a series of imidazo[1,5-b]pyridazines.

Livermore DG, Bethell RC, Cammack N, Hancock AP, Hann MM, Green DV, Lamont RB, Noble SA, Orr DC, Payne JJ, et al. Livermore DG, et al. Among authors: orr dc. J Med Chem. 1993 Nov 26;36(24):3784-94. doi: 10.1021/jm00076a005. J Med Chem. 1993. PMID: 7504733

3

Discovery and analysis of a series of C2-symmetric HIV-1 proteinase inhibitors derived from penicillin.

Gray NM, Cameron JM, Cammack N, Cobley KN, Holmes DS, Humber DC, Orr DC, Penn CR, Potter R, Madar S, et al. Gray NM, et al. Among authors: orr dc. Anal Biochem. 1994 Jan;216(1):89-96. doi: 10.1006/abio.1994.1012. Anal Biochem. 1994. PMID: 8135370

4

A series of penicillin derived C2-symmetric inhibitors of HIV-1 proteinase: synthesis, mode of interaction, and structure-activity relationships.

Humber DC, Bamford MJ, Bethell RC, Cammack N, Cobley K, Evans DN, Gray NM, Hann MM, Orr DC, Saunders J, et al. Humber DC, et al. Among authors: orr dc. J Med Chem. 1993 Oct 15;36(21):3120-8. doi: 10.1021/jm00073a011. J Med Chem. 1993. PMID: 8230098

5

Synthesis and structure-activity relationships of a series of penicillin-derived HIV proteinase inhibitors containing a stereochemically unique peptide isostere.

Holmes DS, Bethell RC, Cammack N, Clemens IR, Kitchin J, McMeekin P, Mo CL, Orr DC, Patel B, Paternoster IL, et al. Holmes DS, et al. Among authors: orr dc. J Med Chem. 1993 Oct 15;36(21):3129-36. doi: 10.1021/jm00073a012. J Med Chem. 1993. PMID: 8230099

6

DNA chain termination activity and inhibition of human immunodeficiency virus reverse transcriptase by carbocyclic 2',3'-didehydro-2',3'-dideoxyguanosine triphosphate.

Orr DC, Figueiredo HT, Mo CL, Penn CR, Cameron JM. Orr DC, et al. J Biol Chem. 1992 Feb 25;267(6):4177-82. J Biol Chem. 1992. PMID: 1371285 Free article.

7

Hydrolysis of a series of synthetic peptide substrates by the human rhinovirus 14 3C proteinase, cloned and expressed in Escherichia coli.

Orr DC, Long AC, Kay J, Dunn BM, Cameron JM. Orr DC, et al. J Gen Virol. 1989 Nov;70 ( Pt 11):2931-42. doi: 10.1099/0022-1317-70-11-2931. J Gen Virol. 1989. PMID: 2555433

8

Effects of (-)-2'-deoxy-3'-thiacytidine (3TC) 5'-triphosphate on human immunodeficiency virus reverse transcriptase and mammalian DNA polymerases alpha, beta, and gamma.

Hart GJ, Orr DC, Penn CR, Figueiredo HT, Gray NM, Boehme RE, Cameron JM. Hart GJ, et al. Among authors: orr dc. Antimicrob Agents Chemother. 1992 Aug;36(8):1688-94. doi: 10.1128/AAC.36.8.1688. Antimicrob Agents Chemother. 1992. PMID: 1384425 Free PMC article.

9

The expression and purification of human rhinovirus protease 3C.

Knott JA, Orr DC, Montgomery DS, Sullivan CA, Weston A. Knott JA, et al. Among authors: orr dc. Eur J Biochem. 1989 Jul 1;182(3):547-55. doi: 10.1111/j.1432-1033.1989.tb14862.x. Eur J Biochem. 1989. PMID: 2546760 Free article.

10

A consensus sequence for substrate hydrolysis by rhinovirus 3C proteinase.

Long AC, Orr DC, Cameron JM, Dunn BM, Kay J. Long AC, et al. Among authors: orr dc. FEBS Lett. 1989 Nov 20;258(1):75-8. doi: 10.1016/0014-5793(89)81619-9. FEBS Lett. 1989. PMID: 2556299 Free article.

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