Quéméner A - Search Results

1

Identification of an interleukin-15alpha receptor-binding site on human interleukin-15.

Bernard J, Harb C, Mortier E, Quéméner A, Meloen RH, Vermot-Desroches C, Wijdeness J, van Dijken P, Grötzinger J, Slootstra JW, Plet A, Jacques Y. Bernard J, et al. Among authors: quemener a. J Biol Chem. 2004 Jun 4;279(23):24313-22. doi: 10.1074/jbc.M312458200. Epub 2004 Mar 23. J Biol Chem. 2004. PMID: 15039446 Free article.

2

Production of recombinant human trimeric CD137L (4-1BBL). Cross-linking is essential to its T cell co-stimulation activity.

Rabu C, Quéméner A, Jacques Y, Echasserieau K, Vusio P, Lang F. Rabu C, et al. Among authors: quemener a. J Biol Chem. 2005 Dec 16;280(50):41472-81. doi: 10.1074/jbc.M506881200. Epub 2005 Oct 4. J Biol Chem. 2005. PMID: 16204238 Free article.

3

Soluble interleukin-15 receptor alpha (IL-15R alpha)-sushi as a selective and potent agonist of IL-15 action through IL-15R beta/gamma. Hyperagonist IL-15 x IL-15R alpha fusion proteins.

Mortier E, Quéméner A, Vusio P, Lorenzen I, Boublik Y, Grötzinger J, Plet A, Jacques Y. Mortier E, et al. Among authors: quemener a. J Biol Chem. 2006 Jan 20;281(3):1612-9. doi: 10.1074/jbc.M508624200. Epub 2005 Nov 11. J Biol Chem. 2006. PMID: 16284400 Free article.

4

Docking of human interleukin-15 to its specific receptor alpha chain: correlation between molecular modeling and mutagenesis experimental data.

Quéméner A, Bernard J, Mortier E, Plet A, Jacques Y, Tran V. Quéméner A, et al. Proteins. 2006 Nov 15;65(3):623-36. doi: 10.1002/prot.21103. Proteins. 2006. PMID: 17001647

5

The exon-3-encoded domain of IL-15ralpha contributes to IL-15 high-affinity binding and is crucial for the IL-15 antagonistic effect of soluble IL-15Ralpha.

Bouchaud G, Garrigue-Antar L, Solé V, Quéméner A, Boublik Y, Mortier E, Perdreau H, Jacques Y, Plet A. Bouchaud G, et al. Among authors: quemener a. J Mol Biol. 2008 Sep 26;382(1):1-12. doi: 10.1016/j.jmb.2008.07.019. Epub 2008 Jul 16. J Mol Biol. 2008. PMID: 18656487

6

High antitumor activity of RLI, an interleukin-15 (IL-15)-IL-15 receptor alpha fusion protein, in metastatic melanoma and colorectal cancer.

Bessard A, Solé V, Bouchaud G, Quéméner A, Jacques Y. Bessard A, et al. Among authors: quemener a. Mol Cancer Ther. 2009 Sep;8(9):2736-45. doi: 10.1158/1535-7163.MCT-09-0275. Epub 2009 Sep 1. Mol Cancer Ther. 2009. PMID: 19723883

7

Evolution of interleukin-15 for higher E. coli expression and solubility.

Béhar G, Solé V, Defontaine A, Maillasson M, Quéméner A, Jacques Y, Tellier C. Béhar G, et al. Among authors: quemener a. Protein Eng Des Sel. 2011 Mar;24(3):283-90. doi: 10.1093/protein/gzq107. Epub 2010 Nov 25. Protein Eng Des Sel. 2011. PMID: 21109548

8

Tumor targeting of the IL-15 superagonist RLI by an anti-GD2 antibody strongly enhances its antitumor potency.

Vincent M, Bessard A, Cochonneau D, Teppaz G, Solé V, Maillasson M, Birklé S, Garrigue-Antar L, Quéméner A, Jacques Y. Vincent M, et al. Among authors: quemener a. Int J Cancer. 2013 Aug 1;133(3):757-65. doi: 10.1002/ijc.28059. Epub 2013 Feb 25. Int J Cancer. 2013. PMID: 23354868

9

Antitumor activity of an immunocytokine composed of an anti-GD2 antibody and the IL-15 superagonist RLI.

Vincent M, Quéméner A, Jacques Y. Vincent M, et al. Among authors: quemener a. Oncoimmunology. 2013 Nov 1;2(11):e26441. doi: 10.4161/onci.26441. Epub 2013 Oct 9. Oncoimmunology. 2013. PMID: 24349876 Free PMC article.

10

Cutting Edge: Differential Fine-Tuning of IL-2- and IL-15-Dependent Functions by Targeting Their Common IL-2/15Rβ/γc Receptor.

Meghnem D, Morisseau S, Frutoso M, Trillet K, Maillasson M, Barbieux I, Khaddage S, Leray I, Hildinger M, Quéméner A, Jacques Y, Mortier E. Meghnem D, et al. Among authors: quemener a. J Immunol. 2017 Jun 15;198(12):4563-4568. doi: 10.4049/jimmunol.1700046. Epub 2017 May 15. J Immunol. 2017. PMID: 28507024

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