Brummelkamp TR - Search Results

1

A large-scale RNAi screen in human cells identifies new components of the p53 pathway.

Berns K, Hijmans EM, Mullenders J, Brummelkamp TR, Velds A, Heimerikx M, Kerkhoven RM, Madiredjo M, Nijkamp W, Weigelt B, Agami R, Ge W, Cavet G, Linsley PS, Beijersbergen RL, Bernards R. Berns K, et al. Among authors: brummelkamp tr. Nature. 2004 Mar 25;428(6981):431-7. doi: 10.1038/nature02371. Nature. 2004. PMID: 15042092

2

TBX-3, the gene mutated in Ulnar-Mammary Syndrome, is a negative regulator of p19ARF and inhibits senescence.

Brummelkamp TR, Kortlever RM, Lingbeek M, Trettel F, MacDonald ME, van Lohuizen M, Bernards R. Brummelkamp TR, et al. J Biol Chem. 2002 Feb 22;277(8):6567-72. doi: 10.1074/jbc.M110492200. Epub 2001 Dec 17. J Biol Chem. 2002. PMID: 11748239 Free article.

3

A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence.

Peeper DS, Shvarts A, Brummelkamp T, Douma S, Koh EY, Daley GQ, Bernards R. Peeper DS, et al. Nat Cell Biol. 2002 Feb;4(2):148-53. doi: 10.1038/ncb742. Nat Cell Biol. 2002. PMID: 11812999

4

A system for stable expression of short interfering RNAs in mammalian cells.

Brummelkamp TR, Bernards R, Agami R. Brummelkamp TR, et al. Science. 2002 Apr 19;296(5567):550-3. doi: 10.1126/science.1068999. Epub 2002 Mar 21. Science. 2002. PMID: 11910072

5

A senescence rescue screen identifies BCL6 as an inhibitor of anti-proliferative p19(ARF)-p53 signaling.

Shvarts A, Brummelkamp TR, Scheeren F, Koh E, Daley GQ, Spits H, Bernards R. Shvarts A, et al. Among authors: brummelkamp tr. Genes Dev. 2002 Mar 15;16(6):681-6. doi: 10.1101/gad.929302. Genes Dev. 2002. PMID: 11914273 Free PMC article.

6

Stable suppression of tumorigenicity by virus-mediated RNA interference.

Brummelkamp TR, Bernards R, Agami R. Brummelkamp TR, et al. Cancer Cell. 2002 Sep;2(3):243-7. doi: 10.1016/s1535-6108(02)00122-8. Cancer Cell. 2002. PMID: 12242156 Free article.

7

Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector.

van de Wetering M, Oving I, Muncan V, Pon Fong MT, Brantjes H, van Leenen D, Holstege FC, Brummelkamp TR, Agami R, Clevers H. van de Wetering M, et al. Among authors: brummelkamp tr. EMBO Rep. 2003 Jun;4(6):609-15. doi: 10.1038/sj.embor.embor865. EMBO Rep. 2003. PMID: 12776180 Free PMC article.

8

Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension.

Lens SM, Wolthuis RM, Klompmaker R, Kauw J, Agami R, Brummelkamp T, Kops G, Medema RH. Lens SM, et al. EMBO J. 2003 Jun 16;22(12):2934-47. doi: 10.1093/emboj/cdg307. EMBO J. 2003. PMID: 12805209 Free PMC article.

9

Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB.

Brummelkamp TR, Nijman SM, Dirac AM, Bernards R. Brummelkamp TR, et al. Nature. 2003 Aug 14;424(6950):797-801. doi: 10.1038/nature01811. Nature. 2003. PMID: 12917690 Free article.

10

New tools for functional mammalian cancer genetics.

Brummelkamp TR, Bernards R. Brummelkamp TR, et al. Nat Rev Cancer. 2003 Oct;3(10):781-9. doi: 10.1038/nrc1191. Nat Rev Cancer. 2003. PMID: 14570045 Review.

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