Harrell JM - Search Results

1

Retrograde transport of the glucocorticoid receptor in neurites requires dynamic assembly of complexes with the protein chaperone hsp90 and is linked to the CHIP component of the machinery for proteasomal degradation.

Galigniana MD, Harrell JM, Housley PR, Patterson C, Fisher SK, Pratt WB. Galigniana MD, et al. Among authors: harrell jm. Brain Res Mol Brain Res. 2004 Apr 7;123(1-2):27-36. doi: 10.1016/j.molbrainres.2003.12.015. Brain Res Mol Brain Res. 2004. PMID: 15046863

2

All of the protein interactions that link steroid receptor.hsp90.immunophilin heterocomplexes to cytoplasmic dynein are common to plant and animal cells.

Harrell JM, Kurek I, Breiman A, Radanyi C, Renoir JM, Pratt WB, Galigniana MD. Harrell JM, et al. Biochemistry. 2002 Apr 30;41(17):5581-7. doi: 10.1021/bi020073q. Biochemistry. 2002. PMID: 11969419

3

Hsp90-binding immunophilins link p53 to dynein during p53 transport to the nucleus.

Galigniana MD, Harrell JM, O'Hagen HM, Ljungman M, Pratt WB. Galigniana MD, et al. Among authors: harrell jm. J Biol Chem. 2004 May 21;279(21):22483-9. doi: 10.1074/jbc.M402223200. Epub 2004 Mar 5. J Biol Chem. 2004. PMID: 15004035 Free article.

4

Pifithrin-alpha inhibits p53 signaling after interaction of the tumor suppressor protein with hsp90 and its nuclear translocation.

Murphy PJ, Galigniana MD, Morishima Y, Harrell JM, Kwok RP, Ljungman M, Pratt WB. Murphy PJ, et al. Among authors: harrell jm. J Biol Chem. 2004 Jul 16;279(29):30195-201. doi: 10.1074/jbc.M403539200. Epub 2004 May 15. J Biol Chem. 2004. PMID: 15145929 Free article.

5

Role of hsp90 and the hsp90-binding immunophilins in signalling protein movement.

Pratt WB, Galigniana MD, Harrell JM, DeFranco DB. Pratt WB, et al. Among authors: harrell jm. Cell Signal. 2004 Aug;16(8):857-72. doi: 10.1016/j.cellsig.2004.02.004. Cell Signal. 2004. PMID: 15157665 Review.

6

Evidence for glucocorticoid receptor transport on microtubules by dynein.

Harrell JM, Murphy PJ, Morishima Y, Chen H, Mansfield JF, Galigniana MD, Pratt WB. Harrell JM, et al. J Biol Chem. 2004 Dec 24;279(52):54647-54. doi: 10.1074/jbc.M406863200. Epub 2004 Oct 13. J Biol Chem. 2004. PMID: 15485845 Free article.

7

Pharmacologic and genetic inhibition of hsp90-dependent trafficking reduces aggregation and promotes degradation of the expanded glutamine androgen receptor without stress protein induction.

Thomas M, Harrell JM, Morishima Y, Peng HM, Pratt WB, Lieberman AP. Thomas M, et al. Among authors: harrell jm. Hum Mol Genet. 2006 Jun 1;15(11):1876-83. doi: 10.1093/hmg/ddl110. Epub 2006 Apr 27. Hum Mol Genet. 2006. PMID: 16644868

8

Binding of hsp90-associated immunophilins to cytoplasmic dynein: direct binding and in vivo evidence that the peptidylprolyl isomerase domain is a dynein interaction domain.

Galigniana MD, Harrell JM, Murphy PJ, Chinkers M, Radanyi C, Renoir JM, Zhang M, Pratt WB. Galigniana MD, et al. Among authors: harrell jm. Biochemistry. 2002 Nov 19;41(46):13602-10. doi: 10.1021/bi020399z. Biochemistry. 2002. PMID: 12427021

9

Androgen receptor acetylation site mutations cause trafficking defects, misfolding, and aggregation similar to expanded glutamine tracts.

Thomas M, Dadgar N, Aphale A, Harrell JM, Kunkel R, Pratt WB, Lieberman AP. Thomas M, et al. Among authors: harrell jm. J Biol Chem. 2004 Feb 27;279(9):8389-95. doi: 10.1074/jbc.M311761200. Epub 2003 Dec 11. J Biol Chem. 2004. PMID: 14670946 Free article.

10

Independent functions of hsp90 in neurotransmitter release and in the continuous synaptic cycling of AMPA receptors.

Gerges NZ, Tran IC, Backos DS, Harrell JM, Chinkers M, Pratt WB, Esteban JA. Gerges NZ, et al. Among authors: harrell jm. J Neurosci. 2004 May 19;24(20):4758-66. doi: 10.1523/JNEUROSCI.0594-04.2004. J Neurosci. 2004. PMID: 15152036 Free PMC article.

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