Simons JW - Search Results

1

Up-regulation of hypoxia-inducible factor 1alpha is an early event in prostate carcinogenesis.

Zhong H, Semenza GL, Simons JW, De Marzo AM. Zhong H, et al. Among authors: simons jw. Cancer Detect Prev. 2004;28(2):88-93. doi: 10.1016/j.cdp.2003.12.009. Cancer Detect Prev. 2004. PMID: 15068831

2

Geldanamycin induces degradation of hypoxia-inducible factor 1alpha protein via the proteosome pathway in prostate cancer cells.

Mabjeesh NJ, Post DE, Willard MT, Kaur B, Van Meir EG, Simons JW, Zhong H. Mabjeesh NJ, et al. Among authors: simons jw. Cancer Res. 2002 May 1;62(9):2478-82. Cancer Res. 2002. PMID: 11980636

3

2ME2 inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF.

Mabjeesh NJ, Escuin D, LaVallee TM, Pribluda VS, Swartz GM, Johnson MS, Willard MT, Zhong H, Simons JW, Giannakakou P. Mabjeesh NJ, et al. Among authors: simons jw. Cancer Cell. 2003 Apr;3(4):363-75. doi: 10.1016/s1535-6108(03)00077-1. Cancer Cell. 2003. PMID: 12726862 Free article.

4

Androgens stimulate hypoxia-inducible factor 1 activation via autocrine loop of tyrosine kinase receptor/phosphatidylinositol 3'-kinase/protein kinase B in prostate cancer cells.

Mabjeesh NJ, Willard MT, Frederickson CE, Zhong H, Simons JW. Mabjeesh NJ, et al. Among authors: simons jw. Clin Cancer Res. 2003 Jul;9(7):2416-25. Clin Cancer Res. 2003. PMID: 12855613

5

Increased expression of hypoxia inducible factor-1alpha in rat and human prostate cancer.

Zhong H, Agani F, Baccala AA, Laughner E, Rioseco-Camacho N, Isaacs WB, Simons JW, Semenza GL. Zhong H, et al. Among authors: simons jw. Cancer Res. 1998 Dec 1;58(23):5280-4. Cancer Res. 1998. PMID: 9850048

6

Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases.

Zhong H, De Marzo AM, Laughner E, Lim M, Hilton DA, Zagzag D, Buechler P, Isaacs WB, Semenza GL, Simons JW. Zhong H, et al. Among authors: simons jw. Cancer Res. 1999 Nov 15;59(22):5830-5. Cancer Res. 1999. PMID: 10582706

7

Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics.

Zhong H, Chiles K, Feldser D, Laughner E, Hanrahan C, Georgescu MM, Simons JW, Semenza GL. Zhong H, et al. Among authors: simons jw. Cancer Res. 2000 Mar 15;60(6):1541-5. Cancer Res. 2000. PMID: 10749120

8

Expression of hypoxia-inducible factor 1alpha in brain tumors: association with angiogenesis, invasion, and progression.

Zagzag D, Zhong H, Scalzitti JM, Laughner E, Simons JW, Semenza GL. Zagzag D, et al. Among authors: simons jw. Cancer. 2000 Jun 1;88(11):2606-18. Cancer. 2000. PMID: 10861440

9

Hypoxia-inducible factor 1alpha and 1beta proteins share common signaling pathways in human prostate cancer cells.

Zhong H, Hanrahan C, van der Poel H, Simons JW. Zhong H, et al. Among authors: simons jw. Biochem Biophys Res Commun. 2001 Jun 8;284(2):352-6. doi: 10.1006/bbrc.2001.4981. Biochem Biophys Res Commun. 2001. PMID: 11394885

10

Dibenzoylmethane, a natural dietary compound, induces HIF-1 alpha and increases expression of VEGF.

Mabjeesh NJ, Willard MT, Harris WB, Sun HY, Wang R, Zhong H, Umbreit JN, Simons JW. Mabjeesh NJ, et al. Among authors: simons jw. Biochem Biophys Res Commun. 2003 Mar 28;303(1):279-86. doi: 10.1016/s0006-291x(03)00336-x. Biochem Biophys Res Commun. 2003. PMID: 12646199

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