The life span determinant p66Shc localizes to mitochondria where it associates with mitochondrial heat shock protein 70 and regulates trans-membrane potential.
Orsini F, Migliaccio E, Moroni M, Contursi C, Raker VA, Piccini D, Martin-Padura I, Pelliccia G, Trinei M, Bono M, Puri C, Tacchetti C, Ferrini M, Mannucci R, Nicoletti I, Lanfrancone L, Giorgio M, Pelicci PG.
Orsini F, et al. Among authors: mannucci r.
J Biol Chem. 2004 Jun 11;279(24):25689-95. doi: 10.1074/jbc.M401844200. Epub 2004 Apr 12.
J Biol Chem. 2004.
PMID: 15078873
Free article.