Bruick RK - Search Results

1

Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis.

Iizuka K, Bruick RK, Liang G, Horton JD, Uyeda K. Iizuka K, et al. Among authors: bruick rk. Proc Natl Acad Sci U S A. 2004 May 11;101(19):7281-6. doi: 10.1073/pnas.0401516101. Epub 2004 Apr 26. Proc Natl Acad Sci U S A. 2004. PMID: 15118080 Free PMC article.

2

A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver.

Yamashita H, Takenoshita M, Sakurai M, Bruick RK, Henzel WJ, Shillinglaw W, Arnot D, Uyeda K. Yamashita H, et al. Among authors: bruick rk. Proc Natl Acad Sci U S A. 2001 Jul 31;98(16):9116-21. doi: 10.1073/pnas.161284298. Epub 2001 Jul 24. Proc Natl Acad Sci U S A. 2001. PMID: 11470916 Free PMC article.

3

The structure of importin α and the nuclear localization peptide of ChREBP, and small compound inhibitors of ChREBP-importin α interactions.

Jung H, Takeshima T, Nakagawa T, MacMillan KS, Wynn RM, Wang H, Sakiyama H, Wei S, Li Y, Bruick RK, Posner BA, De Brabander JK, Uyeda K. Jung H, et al. Among authors: bruick rk. Biochem J. 2020 Sep 18;477(17):3253-3269. doi: 10.1042/BCJ20200520. Biochem J. 2020. PMID: 32776146 Free PMC article.

4

Modulation of HIF-2α PAS-B domain contributes to physiological responses.

Feng Z, Zou X, Chen Y, Wang H, Duan Y, Bruick RK. Feng Z, et al. Among authors: bruick rk. Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):13240-13245. doi: 10.1073/pnas.1810897115. Epub 2018 Dec 6. Proc Natl Acad Sci U S A. 2018. PMID: 30523118 Free PMC article.

5

Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia.

Bruick RK. Bruick RK. Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):9082-7. doi: 10.1073/pnas.97.16.9082. Proc Natl Acad Sci U S A. 2000. PMID: 10922063 Free PMC article.

6

Artificial ligand binding within the HIF2alpha PAS-B domain of the HIF2 transcription factor.

Scheuermann TH, Tomchick DR, Machius M, Guo Y, Bruick RK, Gardner KH. Scheuermann TH, et al. Among authors: bruick rk. Proc Natl Acad Sci U S A. 2009 Jan 13;106(2):450-5. doi: 10.1073/pnas.0808092106. Epub 2009 Jan 7. Proc Natl Acad Sci U S A. 2009. PMID: 19129502 Free PMC article.

7

Structural basis for PAS domain heterodimerization in the basic helix--loop--helix-PAS transcription factor hypoxia-inducible factor.

Erbel PJ, Card PB, Karakuzu O, Bruick RK, Gardner KH. Erbel PJ, et al. Among authors: bruick rk. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15504-9. doi: 10.1073/pnas.2533374100. Epub 2003 Dec 10. Proc Natl Acad Sci U S A. 2003. PMID: 14668441 Free PMC article.

8

Structure of factor-inhibiting hypoxia-inducible factor 1: An asparaginyl hydroxylase involved in the hypoxic response pathway.

Dann CE 3rd, Bruick RK, Deisenhofer J. Dann CE 3rd, et al. Among authors: bruick rk. Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15351-6. doi: 10.1073/pnas.202614999. Epub 2002 Nov 13. Proc Natl Acad Sci U S A. 2002. PMID: 12432100 Free PMC article.

9

The candidate tumor suppressor ING4 represses activation of the hypoxia inducible factor (HIF).

Ozer A, Wu LC, Bruick RK. Ozer A, et al. Among authors: bruick rk. Proc Natl Acad Sci U S A. 2005 May 24;102(21):7481-6. doi: 10.1073/pnas.0502716102. Epub 2005 May 16. Proc Natl Acad Sci U S A. 2005. PMID: 15897452 Free PMC article.

10

Maintaining Mammalian iron and oxygen homeostasis: sensors, regulation, and cross-talk.

Salahudeen AA, Bruick RK. Salahudeen AA, et al. Among authors: bruick rk. Ann N Y Acad Sci. 2009 Oct;1177:30-8. doi: 10.1111/j.1749-6632.2009.05038.x. Ann N Y Acad Sci. 2009. PMID: 19845604 Free PMC article. Review.

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