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GAD1 (2q31.1), which encodes glutamic acid decarboxylase (GAD67), is associated with childhood-onset schizophrenia and cortical gray matter volume loss.
Addington AM, Gornick M, Duckworth J, Sporn A, Gogtay N, Bobb A, Greenstein D, Lenane M, Gochman P, Baker N, Balkissoon R, Vakkalanka RK, Weinberger DR, Rapoport JL, Straub RE. Addington AM, et al. Among authors: straub re. Mol Psychiatry. 2005 Jun;10(6):581-8. doi: 10.1038/sj.mp.4001599. Mol Psychiatry. 2005. PMID: 15505639 Clinical Trial.
Support for association between ADHD and two candidate genes: NET1 and DRD1.
Bobb AJ, Addington AM, Sidransky E, Gornick MC, Lerch JP, Greenstein DK, Clasen LS, Sharp WS, Inoff-Germain G, Wavrant-De Vrièze F, Arcos-Burgos M, Straub RE, Hardy JA, Castellanos FX, Rapoport JL. Bobb AJ, et al. Among authors: straub re. Am J Med Genet B Neuropsychiatr Genet. 2005 Apr 5;134B(1):67-72. doi: 10.1002/ajmg.b.30142. Am J Med Genet B Neuropsychiatr Genet. 2005. PMID: 15717291
Dysbindin (DTNBP1, 6p22.3) is associated with childhood-onset psychosis and endophenotypes measured by the Premorbid Adjustment Scale (PAS).
Gornick MC, Addington AM, Sporn A, Gogtay N, Greenstein D, Lenane M, Gochman P, Ordonez A, Balkissoon R, Vakkalanka R, Weinberger DR, Rapoport JL, Straub RE. Gornick MC, et al. Among authors: straub re. J Autism Dev Disord. 2005 Dec;35(6):831-8. doi: 10.1007/s10803-005-0028-3. J Autism Dev Disord. 2005. PMID: 16283082
173 results