Savi P - Search Results

1

ADP receptor induced activation of guanine nucleotide binding proteins in rat platelet membranes--an effect selectively blocked by the thienopyridine clopidogrel.

Gachet C, Savi P, Ohlmann P, Maffrand JP, Jakobs KH, Cazenave JP. Gachet C, et al. Among authors: savi p. Thromb Haemost. 1992 Jul 6;68(1):79-83. Thromb Haemost. 1992. PMID: 1514178

2

Ticlopidine and clopidogrel (SR 25990C) selectively neutralize ADP inhibition of PGE1-activated platelet adenylate cyclase in rats and rabbits.

Defreyn G, Gachet C, Savi P, Driot F, Cazenave JP, Maffrand JP. Defreyn G, et al. Among authors: savi p. Thromb Haemost. 1991 Feb 12;65(2):186-90. Thromb Haemost. 1991. PMID: 2053105

3

The antiaggregating activity of clopidogrel is due to a metabolic activation by the hepatic cytochrome P450-1A.

Savi P, Combalbert J, Gaich C, Rouchon MC, Maffrand JP, Berger Y, Herbert JM. Savi P, et al. Thromb Haemost. 1994 Aug;72(2):313-7. Thromb Haemost. 1994. PMID: 7831671

4

Binding of [3H]-2-methylthio ADP to rat platelets--effect of clopidogrel and ticlopidine.

Savi P, Laplace MC, Maffrand JP, Herbert JM. Savi P, et al. J Pharmacol Exp Ther. 1994 May;269(2):772-7. J Pharmacol Exp Ther. 1994. PMID: 8182545

5

Identification and biological activity of the active metabolite of clopidogrel.

Savi P, Pereillo JM, Uzabiaga MF, Combalbert J, Picard C, Maffrand JP, Pascal M, Herbert JM. Savi P, et al. Thromb Haemost. 2000 Nov;84(5):891-6. Thromb Haemost. 2000. PMID: 11127873

6

Importance of hepatic metabolism in the antiaggregating activity of the thienopyridine clopidogrel.

Savi P, Herbert JM, Pflieger AM, Dol F, Delebassee D, Combalbert J, Defreyn G, Maffrand JP. Savi P, et al. Biochem Pharmacol. 1992 Aug 4;44(3):527-32. doi: 10.1016/0006-2952(92)90445-o. Biochem Pharmacol. 1992. PMID: 1510701

7

An inherited bleeding disorder linked to a defective interaction between ADP and its receptor on platelets. Its influence on glycoprotein IIb-IIIa complex function.

Nurden P, Savi P, Heilmann E, Bihour C, Herbert JM, Maffrand JP, Nurden A. Nurden P, et al. Among authors: savi p. J Clin Invest. 1995 Apr;95(4):1612-22. doi: 10.1172/JCI117835. J Clin Invest. 1995. PMID: 7706468 Free PMC article.

8

SR 121787, a new orally active fibrinogen receptor antagonist.

Savi P, Badorc A, Lalé A, Bordes MF, Bornia J, Labouret C, Bernat A, de Cointet P, Hoffmann P, Maffrand JP, Herbert JM. Savi P, et al. Thromb Haemost. 1998 Sep;80(3):469-76. Thromb Haemost. 1998. PMID: 9759629

9

Biochemical and pharmacological activities of SR 27417, a highly potent, long-acting platelet-activating factor receptor antagonist.

Herbert JM, Bernat A, Valette G, Gigo V, Lale A, LaPlace MC, Lespy L, Savi P, Maffrand JP, Le Fur G. Herbert JM, et al. Among authors: savi p. J Pharmacol Exp Ther. 1991 Oct;259(1):44-51. J Pharmacol Exp Ther. 1991. PMID: 1656029

10

Structure and stereochemistry of the active metabolite of clopidogrel.

Pereillo JM, Maftouh M, Andrieu A, Uzabiaga MF, Fedeli O, Savi P, Pascal M, Herbert JM, Maffrand JP, Picard C. Pereillo JM, et al. Among authors: savi p. Drug Metab Dispos. 2002 Nov;30(11):1288-95. doi: 10.1124/dmd.30.11.1288. Drug Metab Dispos. 2002. PMID: 12386137

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