Alakhov V - Search Results

1

Phase I dose escalation and pharmacokinetic study of pluronic polymer-bound doxorubicin (SP1049C) in patients with advanced cancer.

Danson S, Ferry D, Alakhov V, Margison J, Kerr D, Jowle D, Brampton M, Halbert G, Ranson M. Danson S, et al. Among authors: alakhov v. Br J Cancer. 2004 Jun 1;90(11):2085-91. doi: 10.1038/sj.bjc.6601856. Br J Cancer. 2004. PMID: 15150584 Free PMC article.

2

A phase 2 study of SP1049C, doxorubicin in P-glycoprotein-targeting pluronics, in patients with advanced adenocarcinoma of the esophagus and gastroesophageal junction.

Valle JW, Armstrong A, Newman C, Alakhov V, Pietrzynski G, Brewer J, Campbell S, Corrie P, Rowinsky EK, Ranson M. Valle JW, et al. Among authors: alakhov v. Invest New Drugs. 2011 Oct;29(5):1029-37. doi: 10.1007/s10637-010-9399-1. Epub 2010 Feb 24. Invest New Drugs. 2011. PMID: 20179989 Clinical Trial.

3

Anthracycline antibiotics non-covalently incorporated into the block copolymer micelles: in vivo evaluation of anti-cancer activity.

Batrakova EV, Dorodnych TY, Klinskii EY, Kliushnenkova EN, Shemchukova OB, Goncharova ON, Arjakov SA, Alakhov VY, Kabanov AV. Batrakova EV, et al. Among authors: alakhov vy. Br J Cancer. 1996 Nov;74(10):1545-52. doi: 10.1038/bjc.1996.587. Br J Cancer. 1996. PMID: 8932333 Free PMC article.

4

Mechanism of sensitization of MDR cancer cells by Pluronic block copolymers: Selective energy depletion.

Batrakova EV, Li S, Elmquist WF, Miller DW, Alakhov VY, Kabanov AV. Batrakova EV, et al. Among authors: alakhov vy. Br J Cancer. 2001 Dec 14;85(12):1987-97. doi: 10.1054/bjoc.2001.2165. Br J Cancer. 2001. PMID: 11747344 Free PMC article.

5

Hypersensitizing effect of pluronic L61 on cytotoxic activity, transport, and subcellular distribution of doxorubicin in multiple drug-resistant cells.

Venne A, Li S, Mandeville R, Kabanov A, Alakhov V. Venne A, et al. Among authors: alakhov v. Cancer Res. 1996 Aug 15;56(16):3626-9. Cancer Res. 1996. PMID: 8705995

6

Pluronic block copolymers for overcoming drug resistance in cancer.

Kabanov AV, Batrakova EV, Alakhov VY. Kabanov AV, et al. Among authors: alakhov vy. Adv Drug Deliv Rev. 2002 Sep 13;54(5):759-79. doi: 10.1016/s0169-409x(02)00047-9. Adv Drug Deliv Rev. 2002. PMID: 12204601 Review.

7

Pluronic block copolymers alter apoptotic signal transduction of doxorubicin in drug-resistant cancer cells.

Minko T, Batrakova EV, Li S, Li Y, Pakunlu RI, Alakhov VY, Kabanov AV. Minko T, et al. Among authors: alakhov vy. J Control Release. 2005 Jul 20;105(3):269-78. doi: 10.1016/j.jconrel.2005.03.019. J Control Release. 2005. PMID: 15939500 Free PMC article.

8

Fundamental relationships between the composition of pluronic block copolymers and their hypersensitization effect in MDR cancer cells.

Batrakova E, Lee S, Li S, Venne A, Alakhov V, Kabanov A. Batrakova E, et al. Among authors: alakhov v. Pharm Res. 1999 Sep;16(9):1373-9. doi: 10.1023/a:1018942823676. Pharm Res. 1999. PMID: 10496652

9

A vascular endothelial growth factor high affinity receptor 1-specific peptide with antiangiogenic activity identified using a phage display peptide library.

El-Mousawi M, Tchistiakova L, Yurchenko L, Pietrzynski G, Moreno M, Stanimirovic D, Ahmad D, Alakhov V. El-Mousawi M, et al. Among authors: alakhov v. J Biol Chem. 2003 Nov 21;278(47):46681-91. doi: 10.1074/jbc.M308681200. Epub 2003 Sep 2. J Biol Chem. 2003. PMID: 12954624 Free article.

10

Multidrug-resistance drug-binding peptides generated by using a phage display library.

Popkov M, Lussier I, Medvedkine V, Estève PO, Alakhov V, Mandeville R. Popkov M, et al. Among authors: alakhov v. Eur J Biochem. 1998 Jan 15;251(1-2):155-63. doi: 10.1046/j.1432-1327.1998.2510155.x. Eur J Biochem. 1998. PMID: 9492279 Free article.

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