Ferry DM - Search Results

1

Aziridinyldinitrobenzamides: synthesis and structure-activity relationships for activation by E. coli nitroreductase.

Helsby NA, Atwell GJ, Yang S, Palmer BD, Anderson RF, Pullen SM, Ferry DM, Hogg A, Wilson WR, Denny WA. Helsby NA, et al. Among authors: ferry dm. J Med Chem. 2004 Jun 3;47(12):3295-307. doi: 10.1021/jm0498699. J Med Chem. 2004. PMID: 15163209

2

Synthesis and evaluation of nitroheterocyclic carbamate prodrugs for use with nitroreductase-mediated gene-directed enzyme prodrug therapy.

Hay MP, Anderson RF, Ferry DM, Wilson WR, Denny WA. Hay MP, et al. Among authors: ferry dm. J Med Chem. 2003 Dec 4;46(25):5533-45. doi: 10.1021/jm030308b. J Med Chem. 2003. PMID: 14640560

3

Mechanism of action and preclinical antitumor activity of the novel hypoxia-activated DNA cross-linking agent PR-104.

Patterson AV, Ferry DM, Edmunds SJ, Gu Y, Singleton RS, Patel K, Pullen SM, Hicks KO, Syddall SP, Atwell GJ, Yang S, Denny WA, Wilson WR. Patterson AV, et al. Among authors: ferry dm. Clin Cancer Res. 2007 Jul 1;13(13):3922-32. doi: 10.1158/1078-0432.CCR-07-0478. Clin Cancer Res. 2007. PMID: 17606726

4

Hypoxia-selective antitumor agents. 13. Effects of acridine substitution on the hypoxia-selective cytotoxicity and metabolic reduction of the bis-bioreductive agent nitracrine N-oxide.

Lee HH, Wilson WR, Ferry DM, van Zijl P, Pullen SM, Denny WA. Lee HH, et al. Among authors: ferry dm. J Med Chem. 1996 Jun 21;39(13):2508-17. doi: 10.1021/jm9600104. J Med Chem. 1996. PMID: 8691448

5

2-Amino metabolites are key mediators of CB 1954 and SN 23862 bystander effects in nitroreductase GDEPT.

Helsby NA, Ferry DM, Patterson AV, Pullen SM, Wilson WR. Helsby NA, et al. Among authors: ferry dm. Br J Cancer. 2004 Mar 8;90(5):1084-92. doi: 10.1038/sj.bjc.6601612. Br J Cancer. 2004. PMID: 14997211 Free PMC article.

6

Pathways of reductive fragmentation of heterocyclic nitroarylmethyl quaternary ammonium prodrugs of mechlorethamine.

Kriste AG, Tercel M, Anderson RF, Ferry DM, Wilson WR. Kriste AG, et al. Among authors: ferry dm. Radiat Res. 2002 Dec;158(6):753-62. doi: 10.1667/0033-7587(2002)158[0753:porfoh]2.0.co;2. Radiat Res. 2002. PMID: 12452778

7

Bystander effects of bioreductive drugs: potential for exploiting pathological tumor hypoxia with dinitrobenzamide mustards.

Wilson WR, Hicks KO, Pullen SM, Ferry DM, Helsby NA, Patterson AV. Wilson WR, et al. Among authors: ferry dm. Radiat Res. 2007 Jun;167(6):625-36. doi: 10.1667/RR0807.1. Radiat Res. 2007. PMID: 17523848

8

DNA cross-links in human tumor cells exposed to the prodrug PR-104A: relationships to hypoxia, bioreductive metabolism, and cytotoxicity.

Singleton RS, Guise CP, Ferry DM, Pullen SM, Dorie MJ, Brown JM, Patterson AV, Wilson WR. Singleton RS, et al. Among authors: ferry dm. Cancer Res. 2009 May 1;69(9):3884-91. doi: 10.1158/0008-5472.CAN-08-4023. Epub 2009 Apr 14. Cancer Res. 2009. PMID: 19366798

9

Cross-bridged cyclen or cyclam Co(III) complexes containing cytotoxic ligands as hypoxia-activated prodrugs.

Chang JY, Lu GL, Stevenson RJ, Brothers PJ, Clark GR, Botting KJ, Ferry DM, Tercel M, Wilson WR, Denny WA, Ware DC. Chang JY, et al. Among authors: ferry dm. Inorg Chem. 2013 Jul 1;52(13):7688-98. doi: 10.1021/ic4006967. Epub 2013 Jun 17. Inorg Chem. 2013. PMID: 23773210

10

Reduction of nitroarylmethyl quaternary ammonium prodrugs of mechlorethamine by radiation.

Wilson WR, Ferry DM, Tercel M, Anderson RF, Denny WA. Wilson WR, et al. Among authors: ferry dm. Radiat Res. 1998 Mar;149(3):237-45. Radiat Res. 1998. PMID: 9496886

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