Klein K - Search Results

1

Genetic polymorphisms in the multidrug resistance-associated protein 3 (ABCC3, MRP3) gene and relationship to its mRNA and protein expression in human liver.

Lang T, Hitzl M, Burk O, Mornhinweg E, Keil A, Kerb R, Klein K, Zanger UM, Eichelbaum M, Fromm MF. Lang T, et al. Among authors: klein k. Pharmacogenetics. 2004 Mar;14(3):155-64. doi: 10.1097/00008571-200403000-00003. Pharmacogenetics. 2004. PMID: 15167703

2

Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver.

Lang T, Klein K, Fischer J, Nüssler AK, Neuhaus P, Hofmann U, Eichelbaum M, Schwab M, Zanger UM. Lang T, et al. Among authors: klein k. Pharmacogenetics. 2001 Jul;11(5):399-415. doi: 10.1097/00008571-200107000-00004. Pharmacogenetics. 2001. PMID: 11470993

3

The genetic determinants of the CYP3A5 polymorphism.

Hustert E, Haberl M, Burk O, Wolbold R, He YQ, Klein K, Nuessler AC, Neuhaus P, Klattig J, Eiselt R, Koch I, Zibat A, Brockmöller J, Halpert JR, Zanger UM, Wojnowski L. Hustert E, et al. Among authors: klein k. Pharmacogenetics. 2001 Dec;11(9):773-9. doi: 10.1097/00008571-200112000-00005. Pharmacogenetics. 2001. PMID: 11740341

4

Discriminative quantification of cytochrome P4502D6 and 2D7/8 pseudogene expression by TaqMan real-time reverse transcriptase polymerase chain reaction.

Endrizzi K, Fischer J, Klein K, Schwab M, Nüssler A, Neuhaus P, Eichelbaum M, Zanger UM. Endrizzi K, et al. Among authors: klein k. Anal Biochem. 2002 Jan 15;300(2):121-31. doi: 10.1006/abio.2001.5453. Anal Biochem. 2002. PMID: 11779102

5

Molecular mechanisms of polymorphic CYP3A7 expression in adult human liver and intestine.

Burk O, Tegude H, Koch I, Hustert E, Wolbold R, Glaeser H, Klein K, Fromm MF, Nuessler AK, Neuhaus P, Zanger UM, Eichelbaum M, Wojnowski L. Burk O, et al. Among authors: klein k. J Biol Chem. 2002 Jul 5;277(27):24280-8. doi: 10.1074/jbc.M202345200. Epub 2002 Apr 8. J Biol Chem. 2002. PMID: 11940601 Free article.

6

Re: modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4.

Wojnowski L, Hustert E, Klein K, Goldammer M, Haberl M, Kirchheiner J, Koch I, Klattig J, Zanger U, Brockmöller J. Wojnowski L, et al. Among authors: klein k. J Natl Cancer Inst. 2002 Apr 17;94(8):630-1; author reply 631-2. doi: 10.1093/jnci/94.8.630. J Natl Cancer Inst. 2002. PMID: 11959896 No abstract available.

7

Genetic polymorphisms of glutathione S-transferase A1, the major glutathione S-transferase in human liver: consequences for enzyme expression and busulfan conjugation.

Bredschneider M, Klein K, Mürdter TE, Marx C, Eichelbaum M, Nüssler AK, Neuhaus P, Zanger UM, Schwab M. Bredschneider M, et al. Among authors: klein k. Clin Pharmacol Ther. 2002 Jun;71(6):479-87. doi: 10.1067/mcp.2002.124518. Clin Pharmacol Ther. 2002. PMID: 12087351

8

A naturally occurring mutation in the SLC21A6 gene causing impaired membrane localization of the hepatocyte uptake transporter.

Michalski C, Cui Y, Nies AT, Nuessler AK, Neuhaus P, Zanger UM, Klein K, Eichelbaum M, Keppler D, Konig J. Michalski C, et al. Among authors: klein k. J Biol Chem. 2002 Nov 8;277(45):43058-63. doi: 10.1074/jbc.M207735200. Epub 2002 Aug 23. J Biol Chem. 2002. PMID: 12196548 Free article.

9

The influence of CYP2B6, CYP2C9 and CYP2D6 genotypes on the formation of the potent antioestrogen Z-4-hydroxy-tamoxifen in human liver.

Coller JK, Krebsfaenger N, Klein K, Endrizzi K, Wolbold R, Lang T, Nüssler A, Neuhaus P, Zanger UM, Eichelbaum M, Mürdter TE. Coller JK, et al. Among authors: klein k. Br J Clin Pharmacol. 2002 Aug;54(2):157-67. doi: 10.1046/j.1365-2125.2002.01614.x. Br J Clin Pharmacol. 2002. PMID: 12207635 Free PMC article.

10

Detection of single nucleotide polymorphisms in CYP2B6 gene.

Zanger UM, Fischer J, Klein K, Lang T. Zanger UM, et al. Among authors: klein k. Methods Enzymol. 2002;357:45-53. doi: 10.1016/s0076-6879(02)57664-3. Methods Enzymol. 2002. PMID: 12424896 No abstract available.

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