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Page 1
Exploration of the P2-P3 SAR of aldehyde cathepsin K inhibitors.
Boros EE, Deaton DN, Hassell AM, McFadyen RB, Miller AB, Miller LR, Paulick MG, Shewchuk LM, Thompson JB, Willard DH Jr, Wright LL. Boros EE, et al. Among authors: wright ll. Bioorg Med Chem Lett. 2004 Jul 5;14(13):3425-9. doi: 10.1016/j.bmcl.2004.04.084. Bioorg Med Chem Lett. 2004. PMID: 15177446
Exploration of the P1 SAR of aldehyde cathepsin K inhibitors.
Catalano JG, Deaton DN, Furfine ES, Hassell AM, McFadyen RB, Miller AB, Miller LR, Shewchuk LM, Willard DH Jr, Wright LL. Catalano JG, et al. Among authors: wright ll. Bioorg Med Chem Lett. 2004 Jan 5;14(1):275-8. doi: 10.1016/j.bmcl.2003.09.088. Bioorg Med Chem Lett. 2004. PMID: 14684342
Design of small molecule ketoamide-based inhibitors of cathepsin K.
Catalano JG, Deaton DN, Long ST, McFadyen RB, Miller LR, Payne JA, Wells-Knecht KJ, Wright LL. Catalano JG, et al. Among authors: wright ll. Bioorg Med Chem Lett. 2004 Feb 9;14(3):719-22. doi: 10.1016/j.bmcl.2003.11.029. Bioorg Med Chem Lett. 2004. PMID: 14741275
Orally bioavailable small molecule ketoamide-based inhibitors of cathepsin K.
Barrett DG, Catalano JG, Deaton DN, Long ST, Miller LR, Tavares FX, Wells-Knecht KJ, Wright LL, Zhou HQ. Barrett DG, et al. Among authors: wright ll. Bioorg Med Chem Lett. 2004 May 17;14(10):2543-6. doi: 10.1016/j.bmcl.2004.02.085. Bioorg Med Chem Lett. 2004. PMID: 15109647
Novel and potent cyclic cyanamide-based cathepsin K inhibitors.
Deaton DN, Hassell AM, McFadyen RB, Miller AB, Miller LR, Shewchuk LM, Tavares FX, Willard DH Jr, Wright LL. Deaton DN, et al. Among authors: wright ll. Bioorg Med Chem Lett. 2005 Apr 1;15(7):1815-9. doi: 10.1016/j.bmcl.2005.02.033. Bioorg Med Chem Lett. 2005. PMID: 15780613
A structural screening approach to ketoamide-based inhibitors of cathepsin K.
Barrett DG, Catalano JG, Deaton DN, Long ST, McFadyen RB, Miller AB, Miller LR, Wells-Knecht KJ, Wright LL. Barrett DG, et al. Among authors: wright ll. Bioorg Med Chem Lett. 2005 May 2;15(9):2209-13. doi: 10.1016/j.bmcl.2005.03.023. Bioorg Med Chem Lett. 2005. PMID: 15837295
351 results