Thierauch KH - Search Results

1

Pharmacologic activity and pharmacokinetics of metabolites of regorafenib in preclinical models.

Zopf D, Fichtner I, Bhargava A, Steinke W, Thierauch KH, Diefenbach K, Wilhelm S, Hafner FT, Gerisch M. Zopf D, et al. Among authors: thierauch kh. Cancer Med. 2016 Nov;5(11):3176-3185. doi: 10.1002/cam4.883. Epub 2016 Oct 13. Cancer Med. 2016. PMID: 27734608 Free PMC article.

2

Regorafenib (BAY 73-4506): antitumor and antimetastatic activities in preclinical models of colorectal cancer.

Schmieder R, Hoffmann J, Becker M, Bhargava A, Müller T, Kahmann N, Ellinghaus P, Adams R, Rosenthal A, Thierauch KH, Scholz A, Wilhelm SM, Zopf D. Schmieder R, et al. Among authors: thierauch kh. Int J Cancer. 2014 Sep 15;135(6):1487-96. doi: 10.1002/ijc.28669. Epub 2014 Apr 17. Int J Cancer. 2014. PMID: 24347491 Free PMC article.

3

Inhibition of hypoxia-induced gene transcription by substituted pyrazolyl oxadiazoles: initial lead generation and structure-activity relationships.

Härter M, Thierauch KH, Boyer S, Bhargava A, Ellinghaus P, Beck H, Greschat-Schade S, Hess-Stumpp H, Unterschemmann K. Härter M, et al. Among authors: thierauch kh. ChemMedChem. 2014 Jan;9(1):61-6. doi: 10.1002/cmdc.201300357. Epub 2013 Nov 27. ChemMedChem. 2014. PMID: 24285584

4

Angiopoietin-2 drives lymphatic metastasis of pancreatic cancer.

Schulz P, Fischer C, Detjen KM, Rieke S, Hilfenhaus G, von Marschall Z, Böhmig M, Koch I, Kehrberger J, Hauff P, Thierauch KH, Alves F, Wiedenmann B, Scholz A. Schulz P, et al. Among authors: thierauch kh. FASEB J. 2011 Oct;25(10):3325-35. doi: 10.1096/fj.11-182287. Epub 2011 Jun 17. FASEB J. 2011. PMID: 21685330

5

LDH-A influences hypoxia-inducible factor 1α (HIF1 α) and is critical for growth of HT29 colon carcinoma cells in vivo.

Langhammer S, Najjar M, Hess-Stumpp H, Thierauch KH. Langhammer S, et al. Among authors: thierauch kh. Target Oncol. 2011 Sep;6(3):155-62. doi: 10.1007/s11523-011-0184-7. Epub 2011 Jun 10. Target Oncol. 2011. PMID: 21660559

6

Regorafenib (BAY 73-4506): a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity.

Wilhelm SM, Dumas J, Adnane L, Lynch M, Carter CA, Schütz G, Thierauch KH, Zopf D. Wilhelm SM, et al. Among authors: thierauch kh. Int J Cancer. 2011 Jul 1;129(1):245-55. doi: 10.1002/ijc.25864. Epub 2011 Apr 22. Int J Cancer. 2011. PMID: 21170960

7

Inflammatory corneal (lymph)angiogenesis is blocked by VEGFR-tyrosine kinase inhibitor ZK 261991, resulting in improved graft survival after corneal transplantation.

Hos D, Bock F, Dietrich T, Onderka J, Kruse FE, Thierauch KH, Cursiefen C. Hos D, et al. Among authors: thierauch kh. Invest Ophthalmol Vis Sci. 2008 May;49(5):1836-42. doi: 10.1167/iovs.07-1314. Invest Ophthalmol Vis Sci. 2008. PMID: 18436817

8

Vascular endothelial growth factor-D induces lymphangiogenesis and lymphatic metastasis in models of ductal pancreatic cancer.

Von Marschall Z, Scholz A, Stacker SA, Achen MG, Jackson DG, Alves F, Schirner M, Haberey M, Thierauch KH, Wiedenmann B, Rosewicz S. Von Marschall Z, et al. Among authors: thierauch kh. Int J Oncol. 2005 Sep;27(3):669-79. Int J Oncol. 2005. PMID: 16077915

9

PTK 787/ZK 222584, a tyrosine kinase inhibitor of all known VEGF receptors, represses tumor growth with high efficacy.

Hess-Stumpp H, Haberey M, Thierauch KH. Hess-Stumpp H, et al. Among authors: thierauch kh. Chembiochem. 2005 Mar;6(3):550-7. doi: 10.1002/cbic.200400305. Chembiochem. 2005. PMID: 15742376

10

Shift of syndecan-1 expression from epithelial to stromal cells during progression of solid tumours.

Mennerich D, Vogel A, Klaman I, Dahl E, Lichtner RB, Rosenthal A, Pohlenz HD, Thierauch KH, Sommer A. Mennerich D, et al. Among authors: thierauch kh. Eur J Cancer. 2004 Jun;40(9):1373-82. doi: 10.1016/j.ejca.2004.01.038. Eur J Cancer. 2004. PMID: 15177497

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