Williams LE - Search Results

1

Characterization of engineered anti-p185HER-2 (scFv-CH3)2 antibody fragments (minibodies) for tumor targeting.

Olafsen T, Tan GJ, Cheung CW, Yazaki PJ, Park JM, Shively JE, Williams LE, Raubitschek AA, Press MF, Wu AM. Olafsen T, et al. Among authors: williams le. Protein Eng Des Sel. 2004 Apr;17(4):315-23. doi: 10.1093/protein/gzh040. Epub 2004 Jun 8. Protein Eng Des Sel. 2004. PMID: 15187222

2

124I-labeled engineered anti-CEA minibodies and diabodies allow high-contrast, antigen-specific small-animal PET imaging of xenografts in athymic mice.

Sundaresan G, Yazaki PJ, Shively JE, Finn RD, Larson SM, Raubitschek AA, Williams LE, Chatziioannou AF, Gambhir SS, Wu AM. Sundaresan G, et al. Among authors: williams le. J Nucl Med. 2003 Dec;44(12):1962-9. J Nucl Med. 2003. PMID: 14660722 Free PMC article.

3

Covalent disulfide-linked anti-CEA diabody allows site-specific conjugation and radiolabeling for tumor targeting applications.

Olafsen T, Cheung CW, Yazaki PJ, Li L, Sundaresan G, Gambhir SS, Sherman MA, Williams LE, Shively JE, Raubitschek AA, Wu AM. Olafsen T, et al. Among authors: williams le. Protein Eng Des Sel. 2004 Jan;17(1):21-7. doi: 10.1093/protein/gzh009. Protein Eng Des Sel. 2004. PMID: 14985534 Free PMC article.

4

Humanization of the anti-CEA T84.66 antibody based on crystal structure data.

Yazaki PJ, Sherman MA, Shively JE, Ikle D, Williams LE, Wong JY, Colcher D, Wu AM, Raubitschek AA. Yazaki PJ, et al. Among authors: williams le. Protein Eng Des Sel. 2004 May;17(5):481-9. doi: 10.1093/protein/gzh056. Epub 2004 Aug 17. Protein Eng Des Sel. 2004. PMID: 15316127

5

Optimizing radiolabeled engineered anti-p185HER2 antibody fragments for in vivo imaging.

Olafsen T, Kenanova VE, Sundaresan G, Anderson AL, Crow D, Yazaki PJ, Li L, Press MF, Gambhir SS, Williams LE, Wong JY, Raubitschek AA, Shively JE, Wu AM. Olafsen T, et al. Among authors: williams le. Cancer Res. 2005 Jul 1;65(13):5907-16. doi: 10.1158/0008-5472.CAN-04-4472. Cancer Res. 2005. PMID: 15994969 Free PMC article.

6

Tuning the serum persistence of human serum albumin domain III:diabody fusion proteins.

Kenanova VE, Olafsen T, Salazar FB, Williams LE, Knowles S, Wu AM. Kenanova VE, et al. Among authors: williams le. Protein Eng Des Sel. 2010 Oct;23(10):789-98. doi: 10.1093/protein/gzq054. Epub 2010 Aug 28. Protein Eng Des Sel. 2010. PMID: 20802234 Free PMC article.

7

Tailoring the pharmacokinetics and positron emission tomography imaging properties of anti-carcinoembryonic antigen single-chain Fv-Fc antibody fragments.

Kenanova V, Olafsen T, Crow DM, Sundaresan G, Subbarayan M, Carter NH, Ikle DN, Yazaki PJ, Chatziioannou AF, Gambhir SS, Williams LE, Shively JE, Colcher D, Raubitschek AA, Wu AM. Kenanova V, et al. Among authors: williams le. Cancer Res. 2005 Jan 15;65(2):622-31. Cancer Res. 2005. PMID: 15695407 Free PMC article.

8

Radioiodinated versus radiometal-labeled anti-carcinoembryonic antigen single-chain Fv-Fc antibody fragments: optimal pharmacokinetics for therapy.

Kenanova V, Olafsen T, Williams LE, Ruel NH, Longmate J, Yazaki PJ, Shively JE, Colcher D, Raubitschek AA, Wu AM. Kenanova V, et al. Among authors: williams le. Cancer Res. 2007 Jan 15;67(2):718-26. doi: 10.1158/0008-5472.CAN-06-0454. Cancer Res. 2007. PMID: 17234783

9

PET imaging of colorectal cancer in xenograft-bearing mice by use of an 18F-labeled T84.66 anti-carcinoembryonic antigen diabody.

Cai W, Olafsen T, Zhang X, Cao Q, Gambhir SS, Williams LE, Wu AM, Chen X. Cai W, et al. Among authors: williams le. J Nucl Med. 2007 Feb;48(2):304-10. J Nucl Med. 2007. PMID: 17268029 Free article.

10

Combined radioimmunotherapy and chemotherapy of breast tumors with Y-90-labeled anti-Her2 and anti-CEA antibodies with taxol.

Crow DM, Williams L, Colcher D, Wong JY, Raubitschek A, Shively JE. Crow DM, et al. Bioconjug Chem. 2005 Sep-Oct;16(5):1117-25. doi: 10.1021/bc0500948. Bioconjug Chem. 2005. PMID: 16173788

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