Fielder PJ - Search Results

1

In vitro internalization, intracellular transport, and clearance of an anti-CD11a antibody (Raptiva) by human T-cells.

Coffey GP, Stefanich E, Palmieri S, Eckert R, Padilla-Eagar J, Fielder PJ, Pippig S. Coffey GP, et al. Among authors: fielder pj. J Pharmacol Exp Ther. 2004 Sep;310(3):896-904. doi: 10.1124/jpet.104.067611. Epub 2004 Jun 9. J Pharmacol Exp Ther. 2004. PMID: 15190122

2

Tissue distribution and receptor-mediated clearance of anti-CD11a antibody in mice.

Coffey GP, Fox JA, Pippig S, Palmieri S, Reitz B, Gonzales M, Bakshi A, Padilla-Eagar J, Fielder PJ. Coffey GP, et al. Among authors: fielder pj. Drug Metab Dispos. 2005 May;33(5):623-9. doi: 10.1124/dmd.104.002584. Epub 2005 Jan 26. Drug Metab Dispos. 2005. PMID: 15673599

3

Translational pharmacokinetics and pharmacodynamics of an FcRn-variant anti-CD4 monoclonal antibody from preclinical model to phase I study.

Zheng Y, Scheerens H, Davis JC Jr, Deng R, Fischer SK, Woods C, Fielder PJ, Stefanich EG. Zheng Y, et al. Among authors: fielder pj. Clin Pharmacol Ther. 2011 Feb;89(2):283-90. doi: 10.1038/clpt.2010.311. Epub 2010 Dec 29. Clin Pharmacol Ther. 2011. PMID: 21191378 Clinical Trial.

4

Pharmacokinetics/pharmacodynamics of nondepleting anti-CD4 monoclonal antibody (TRX1) in healthy human volunteers.

Ng CM, Stefanich E, Anand BS, Fielder PJ, Vaickus L. Ng CM, et al. Among authors: fielder pj. Pharm Res. 2006 Jan;23(1):95-103. doi: 10.1007/s11095-005-8814-3. Epub 2006 Nov 30. Pharm Res. 2006. PMID: 16308668

5

Evidence for an asialoglycoprotein receptor on nonparenchymal cells for O-linked glycoproteins.

Stefanich EG, Ren S, Danilenko DM, Lim A, Song A, Iyer S, Fielder PJ. Stefanich EG, et al. Among authors: fielder pj. J Pharmacol Exp Ther. 2008 Nov;327(2):308-15. doi: 10.1124/jpet.108.142232. Epub 2008 Aug 26. J Pharmacol Exp Ther. 2008. PMID: 18728239

6

Effect of antigen binding affinity and effector function on the pharmacokinetics and pharmacodynamics of anti-IgE monoclonal antibodies.

Mortensen DL, Prabhu S, Stefanich EG, Kadkhodayan-Fischer S, Gelzleichter TR, Baker D, Jiang J, Wallace K, Iyer S, Fielder PJ, Putnam WS. Mortensen DL, et al. Among authors: fielder pj. MAbs. 2012 Nov-Dec;4(6):724-31. doi: 10.4161/mabs.22216. MAbs. 2012. PMID: 23778267 Free PMC article.

7

Dose schedule of recombinant murine thrombopoietin prior to myelosuppressive and myeloablative therapy in mice.

Stefanich EG, Carlson-Zermeno CC, McEvoy K, Reich M, Fielder PJ. Stefanich EG, et al. Among authors: fielder pj. Cancer Chemother Pharmacol. 2001;47(1):70-7. doi: 10.1007/s002800000203. Cancer Chemother Pharmacol. 2001. PMID: 11221965

8

Human platelets as a model for the binding and degradation of thrombopoietin.

Fielder PJ, Hass P, Nagel M, Stefanich E, Widmer R, Bennett GL, Keller GA, de Sauvage FJ, Eaton D. Fielder PJ, et al. Blood. 1997 Apr 15;89(8):2782-8. Blood. 1997. PMID: 9108396 Free article.

9

Metabolism of thrombopoietin (TPO) in vivo: determination of the binding dynamics for TPO in mice.

Stefanich E, Senn T, Widmer R, Fratino C, Keller GA, Fielder PJ. Stefanich E, et al. Among authors: fielder pj. Blood. 1997 Jun 1;89(11):4063-70. Blood. 1997. PMID: 9166846 Free article.

10

Regulation of thrombopoietin levels by c-mpl-mediated binding to platelets.

Fielder PJ, Gurney AL, Stefanich E, Marian M, Moore MW, Carver-Moore K, de Sauvage FJ. Fielder PJ, et al. Blood. 1996 Mar 15;87(6):2154-61. Blood. 1996. PMID: 8630374 Free article.

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